Chapter title |
A Chemical Mutagenesis Screen Identifies Mouse Models with ERG Defects
|
---|---|
Chapter number | 24 |
Book title |
Retinal Degenerative Diseases
|
Published in |
Advances in experimental medicine and biology, January 2016
|
DOI | 10.1007/978-3-319-17121-0_24 |
Pubmed ID | |
Book ISBNs |
978-3-31-917120-3, 978-3-31-917121-0
|
Authors |
Jeremy R. Charette, Ivy S. Samuels, Minzhong Yu, Lisa Stone, Wanda Hicks, Lan Ying Shi, Mark P. Krebs, Jürgen K. Naggert, Patsy M. Nishina, Neal S. Peachey, Charette, Jeremy R., Samuels, Ivy S., Yu, Minzhong, Stone, Lisa, Hicks, Wanda, Shi, Lan Ying, Krebs, Mark P., Naggert, Jürgen K., Nishina, Patsy M., Peachey, Neal S. |
Abstract |
Mouse models provide important resources for many areas of vision research, pertaining to retinal development, retinal function and retinal disease. The Translational Vision Research Models (TVRM) program uses chemical mutagenesis to generate new mouse models for vision research. In this chapter, we report the identification of mouse models for Grm1, Grk1 and Lrit3. Each of these is characterized by a primary defect in the electroretinogram. All are available without restriction to the research community. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 7 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 2 | 29% |
Student > Master | 2 | 29% |
Student > Postgraduate | 1 | 14% |
Researcher | 1 | 14% |
Unknown | 1 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 3 | 43% |
Biochemistry, Genetics and Molecular Biology | 1 | 14% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 14% |
Unknown | 2 | 29% |