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Chapter title |
Gene Expression Analysis of CCN Protein in Bone Under Mechanical Stress.
|
---|---|
Chapter number | 26 |
Book title |
CCN Proteins
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Published in |
Methods in molecular biology, January 2017
|
DOI | 10.1007/978-1-4939-6430-7_26 |
Pubmed ID | |
Book ISBNs |
978-1-4939-6428-4, 978-1-4939-6430-7
|
Authors |
Teruko Takano-Yamamoto D.D.S., Ph.D., Tomohiro Fukunaga, Nobuo Takeshita, Teruko Takano-Yamamoto |
Editors |
Masaharu Takigawa |
Abstract |
To investigate mechanical-dependent bone remodeling, we had previously applied various types of mechanical loading onto the teeth of rats and mice. In vitro cultured bone cells were then used to elucidate the mechanisms underlying the specific phenomenon revealed by in vivo experiments. This review describes the techniques used to upregulate CCN2 expression in bone cells produced by different types of mechanical stress, such as fluid shear stress and substrate strain in vitro, and compression or tension force in vivo. |
Mendeley readers
The data shown below were compiled from readership statistics for 10 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 10 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Postgraduate | 4 | 40% |
Student > Ph. D. Student | 1 | 10% |
Lecturer | 1 | 10% |
Student > Bachelor | 1 | 10% |
Unknown | 3 | 30% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 6 | 60% |
Engineering | 1 | 10% |
Unknown | 3 | 30% |