Chapter title |
Can the Assessment of Spontaneous Oscillations by Near Infrared Spectrophotometry Predict Neurological Outcome of Preterm Infants?
|
---|---|
Chapter number | 65 |
Book title |
Oxygen Transport to Tissue XXXVII
|
Published in |
Advances in experimental medicine and biology, January 2016
|
DOI | 10.1007/978-1-4939-3023-4_65 |
Pubmed ID | |
Book ISBNs |
978-1-4939-3022-7, 978-1-4939-3023-4
|
Authors |
André Stammwitz, Kurt von Siebenthal, Hans U. Bucher, Martin Wolf |
Editors |
Clare E. Elwell, Terence S. Leung, David K. Harrison |
Abstract |
The aim was to assess the correlation between cerebral autoregulation and outcome. Included were 31 preterm infants, gestational age 26 1/7 to 32 2/7 and <24 h life. Coherence between cerebral total haemoglobin (tHb) or oxygenation index (OI) measured by near-infrared spectrophotometry (NIRS) and systemic heart rate (HR) or arterial blood pressure (MAP) was calculated as a measure of autoregulation. In contrast to previous studies, low coherences in the first 24 h were significantly associated with intraventricular haemorrhage, death or abnormal neurodevelopmental outcome at 18 months or later. We suggest that our results can be explained by the concept of a multi-oscillatory-functions-order. |
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