Chapter title |
Near-Infrared Image Reconstruction of Newborns' Brains: Robustness to Perturbations of the Source/Detector Location.
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Chapter number | 47 |
Book title |
Oxygen Transport to Tissue XXXVII
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Published in |
Advances in experimental medicine and biology, January 2016
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DOI | 10.1007/978-1-4939-3023-4_47 |
Pubmed ID | |
Book ISBNs |
978-1-4939-3022-7, 978-1-4939-3023-4
|
Authors |
L. Ahnen, M. Wolf, C. Hagmann, S. Sanchez |
Editors |
Clare E. Elwell, Terence S. Leung, David K. Harrison |
Abstract |
The brain of preterm infants is the most vulnerable organ and can be severely injured by cerebral ischemia. We are working on a near-infrared imager to early detect cerebral ischemia. During imaging of the brain, movements of the newborn infants are inevitable and the near-infrared sensor has to be able to function on irregular geometries. Our aim is to determine the robustness of the near-infrared image reconstruction to small variations of the source and detector locations. In analytical and numerical simulations, the error estimations for a homogeneous medium agree well. The worst case estimates of errors in reduced scattering and absorption coefficient for distances of r = 40 mm are acceptable for a single source-detector pair. The optical properties of an inhomogeneity representing an ischemia are reconstructed correctly within a homogeneous medium, if the error in placement is random. |
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Student > Bachelor | 1 | 20% |
Researcher | 1 | 20% |
Unknown | 1 | 20% |
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