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Mendeley readers
Chapter title |
Possibilities of Using Fetal Hemoglobin as a Platform for Producing Hemoglobin-Based Oxygen Carriers (HBOCs).
|
---|---|
Chapter number | 56 |
Book title |
Oxygen Transport to Tissue XXXVII
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Published in |
Advances in experimental medicine and biology, January 2016
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DOI | 10.1007/978-1-4939-3023-4_56 |
Pubmed ID | |
Book ISBNs |
978-1-4939-3022-7, 978-1-4939-3023-4
|
Authors |
Khuanpiroon Ratanasopa, Tommy Cedervall, Leif Bülow |
Editors |
Clare E. Elwell, Terence S. Leung, David K. Harrison |
Abstract |
The expression levels of fetal hemoglobin (HbF) in bacterial recombinant systems are higher compared with normal adult hemoglobin (HbA). However, heme disorientation in globins are often observed in recombinant production processes, both for HbA and HbF, although the degree of heme oriental disorder is much lower for HbF. In addition, the heme disorientation can be converted to a normal conformation by an oxidation-reduction process. A chromatographic cleaning process involving a strong anion exchanger can be utilized to remove such unstable and nondesirable forms of Hb. |
Mendeley readers
The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 15 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 3 | 20% |
Student > Bachelor | 3 | 20% |
Student > Ph. D. Student | 2 | 13% |
Student > Master | 1 | 7% |
Other | 1 | 7% |
Other | 0 | 0% |
Unknown | 5 | 33% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 3 | 20% |
Chemical Engineering | 2 | 13% |
Chemistry | 1 | 7% |
Medicine and Dentistry | 1 | 7% |
Unknown | 8 | 53% |