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Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity

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Cover of 'Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Epidemiology of Gender Differences in Diabetes and Obesity
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    Chapter 2 Sex Differences in Body Composition
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    Chapter 3 Cellular Mechanisms Driving Sex Differences in Adipose Tissue Biology and Body Shape in Humans and Mouse Models
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    Chapter 4 Men Are from Mars, Women Are from Venus: Sex Differences in Insulin Action and Secretion
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    Chapter 5 The Role of Sex and Sex Hormones in Regulating Obesity-Induced Inflammation
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    Chapter 6 Sex Differences in Leptin Control of Cardiovascular Function in Health and Metabolic Diseases
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    Chapter 7 Sex Effects at the Ramparts: Nutrient- and Microbe-Mediated Regulation of the Immune-Metabolic Interface
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    Chapter 8 Sexual Dimorphism and Estrogen Action in Mouse Liver
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    Chapter 9 Sex Differences in Muscle Wasting
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    Chapter 10 Origins and Functions of the Ventrolateral VMH: A Complex Neuronal Cluster Orchestrating Sex Differences in Metabolism and Behavior
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    Chapter 11 Menopause, Estrogens, and Glucose Homeostasis in Women
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    Chapter 12 Role of Estrogens in the Regulation of Liver Lipid Metabolism
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    Chapter 13 The Role of Skeletal Muscle Estrogen Receptors in Metabolic Homeostasis and Insulin Sensitivity
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    Chapter 14 Estrogens and Body Weight Regulation in Men
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    Chapter 15 Estradiol Regulation of Brown Adipose Tissue Thermogenesis
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    Chapter 16 Brain Estrogens and Feeding Behavior
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    Chapter 17 Sex Differences and Role of Estradiol in Hypoglycemia-Associated Counter-Regulation
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    Chapter 18 The Role of Estrogens in Pancreatic Islet Physiopathology
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    Chapter 19 Nuclear and Membrane Actions of Estrogen Receptor Alpha: Contribution to the Regulation of Energy and Glucose Homeostasis
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    Chapter 20 G-Protein-Coupled Estrogen Receptor (GPER) and Sex-Specific Metabolic Homeostasis
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    Chapter 21 Sex-Dependent Role of Estrogen Sulfotransferase and Steroid Sulfatase in Metabolic Homeostasis
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    Chapter 22 Negative Impact of Testosterone Deficiency and 5α-Reductase Inhibitors Therapy on Metabolic and Sexual Function in Men
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    Chapter 23 Testosterone Therapy and Glucose Homeostasis in Men with Testosterone Deficiency (Hypogonadism)
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    Chapter 24 Sex Differences in Androgen Regulation of Metabolism in Nonhuman Primates
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    Chapter 25 Prenatal Testosterone Programming of Insulin Resistance in the Female Sheep
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    Chapter 26 The Role of Androgen Excess in Metabolic Dysfunction in Women
  28. Altmetric Badge
    Chapter 27 Sex, Gender, and Transgender: Metabolic Impact of Cross Hormone Therapy
Attention for Chapter 13: The Role of Skeletal Muscle Estrogen Receptors in Metabolic Homeostasis and Insulin Sensitivity
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Chapter title
The Role of Skeletal Muscle Estrogen Receptors in Metabolic Homeostasis and Insulin Sensitivity
Chapter number 13
Book title
Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity
Published in
Advances in experimental medicine and biology, January 2017
DOI 10.1007/978-3-319-70178-3_13
Pubmed ID
Book ISBNs
978-3-31-970177-6, 978-3-31-970178-3
Authors

Andrea L. Hevener, Zhenqi Zhou, Brian G. Drew, Vicent Ribas, Hevener, Andrea L., Zhou, Zhenqi, Drew, Brian G., Ribas, Vicent

Abstract

Women in the modern era are challenged with facing menopausal symptoms as well as heightened disease risk associated with increasing adiposity and metabolic dysfunction for up to three decades of life. Treatment strategies to combat metabolic dysfunction and associated pathologies have been hampered by our lack of understanding regarding the biological causes of these clinical conditions and our incomplete understanding regarding the effects of estrogens and the tissue-specific functions and molecular actions of its receptors. In this chapter we provide evidence supporting a critical and protective role for skeletal muscle estrogen receptor α in the maintenance of metabolic homeostasis and insulin sensitivity. Studies identifying the critical ER-regulated pathways essential for disease prevention will lay the important foundation for the rational design of novel therapeutic strategies to improve the health of women while limiting secondary complications that have plagued traditional hormone replacement interventions.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 27 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 11%
Student > Doctoral Student 3 11%
Student > Master 3 11%
Professor 2 7%
Researcher 2 7%
Other 4 15%
Unknown 10 37%
Readers by discipline Count As %
Agricultural and Biological Sciences 4 15%
Biochemistry, Genetics and Molecular Biology 3 11%
Medicine and Dentistry 3 11%
Nursing and Health Professions 2 7%
Computer Science 1 4%
Other 4 15%
Unknown 10 37%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 July 2018.
All research outputs
#18,578,649
of 23,011,300 outputs
Outputs from Advances in experimental medicine and biology
#3,325
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Outputs of similar age
#311,468
of 421,287 outputs
Outputs of similar age from Advances in experimental medicine and biology
#333
of 490 outputs
Altmetric has tracked 23,011,300 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,960 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.1. This one is in the 19th percentile – i.e., 19% of its peers scored the same or lower than it.
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We're also able to compare this research output to 490 others from the same source and published within six weeks on either side of this one. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.