Zebrafish
Humana Press
Chapter title |
Construction of the Inbred Strain
|
---|---|
Chapter number | 8 |
Book title |
Zebrafish
|
Published in |
Methods in molecular biology, January 2016
|
DOI | 10.1007/978-1-4939-3771-4_8 |
Pubmed ID | |
Book ISBNs |
978-1-4939-3769-1, 978-1-4939-3771-4
|
Authors |
Minori Shinya |
Abstract |
Genetically homogeneous populations such as inbred strains are valuable experimental tools in various fields of biomedical analyses. In many animals, inbred strains are established by consecutive sib-pair mating for a minimum of 20 generations. As the generation proceeds, fitness of the population reduces usually. Therefore, in order to establish inbred strains, the important point is the selection of pairs in good condition at each generation. Here, I describe the procedure and tips for generating inbred strains in zebrafish. |
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Unknown | 5 | 100% |
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 1 | 20% |
Student > Bachelor | 1 | 20% |
Researcher | 1 | 20% |
Unknown | 2 | 40% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 1 | 20% |
Agricultural and Biological Sciences | 1 | 20% |
Unknown | 3 | 60% |