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Interrelations between Essential Metal Ions and Human Diseases

Overview of attention for book
Attention for Chapter 16: Selenium. Role of the Essential Metalloid in Health
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About this Attention Score

  • Among the highest-scoring outputs from this source (#47 of 134)
  • Average Attention Score compared to outputs of the same age

Mentioned by

wikipedia
1 Wikipedia page

Citations

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173 Dimensions

Readers on

mendeley
77 Mendeley
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Chapter title
Selenium. Role of the Essential Metalloid in Health
Chapter number 16
Book title
Interrelations between Essential Metal Ions and Human Diseases
Published in
Metal ions in life sciences, November 2013
DOI 10.1007/978-94-007-7500-8_16
Pubmed ID
Book ISBNs
978-9-40-077499-5, 978-9-40-077500-8
Authors

Suguru Kurokawa, Marla J. Berry

Editors

Astrid Sigel, Helmut Sigel, Roland K.O. Sigel

Abstract

Selenium is an essential micronutrient in mammals, but is also recognized as toxic in excess. It is a non-metal with properties that are intermediate between the chalcogen elements sulfur and tellurium. Selenium exerts its biological functions through selenoproteins. Selenoproteins contain selenium in the form of the 21st amino acid, selenocysteine (Sec), which is an analog of cysteine with the sulfur-containing side chain replaced by a Se-containing side chain. Sec is encoded by the codon UGA, which is one of three termination codons for mRNA translation in non-selenoprotein genes. Recognition of the UGA codon as a Sec insertion site instead of stop requires a Sec insertion sequence (SECIS) element in selenoprotein mRNAs and a unique selenocysteyl-tRNA, both of which are recognized by specialized protein factors. Unlike the 20 standard amino acids, Sec is biosynthesized from serine on its tRNA. Twenty-five selenoproteins are encoded in the human genome. Most of the selenoprotein genes were discovered by bioinformatics approaches, searching for SECIS elements downstream of in-frame UGA codons. Sec has been described as having stronger nucleophilic and electrophilic properties than cysteine, and Sec is present in the catalytic site of all selenoenzymes. Most selenoproteins, whose functions are known, are involved in redox systems and signaling pathways. However, several selenoproteins are not well characterized in terms of their function. The selenium field has grown dramatically in the last few decades, and research on selenium biology is providing extensive new information regarding its importance for human health.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 77 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 77 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 13 17%
Student > Ph. D. Student 10 13%
Student > Bachelor 9 12%
Researcher 8 10%
Student > Doctoral Student 5 6%
Other 5 6%
Unknown 27 35%
Readers by discipline Count As %
Agricultural and Biological Sciences 8 10%
Medicine and Dentistry 8 10%
Pharmacology, Toxicology and Pharmaceutical Science 8 10%
Biochemistry, Genetics and Molecular Biology 7 9%
Nursing and Health Professions 5 6%
Other 9 12%
Unknown 32 42%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 July 2014.
All research outputs
#7,454,951
of 22,790,780 outputs
Outputs from Metal ions in life sciences
#47
of 134 outputs
Outputs of similar age
#90,789
of 302,395 outputs
Outputs of similar age from Metal ions in life sciences
#11
of 19 outputs
Altmetric has tracked 22,790,780 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 134 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.1. This one is in the 5th percentile – i.e., 5% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 302,395 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 49th percentile – i.e., 49% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.