Chapter title |
Cobalt: Its Role in Health and Disease
|
---|---|
Chapter number | 9 |
Book title |
Interrelations between Essential Metal Ions and Human Diseases
|
Published in |
Metal ions in life sciences, November 2013
|
DOI | 10.1007/978-94-007-7500-8_9 |
Pubmed ID | |
Book ISBNs |
978-9-40-077499-5, 978-9-40-077500-8
|
Authors |
Kazuhiro Yamada, Yamada, Kazuhiro |
Editors |
Astrid Sigel, Helmut Sigel, Roland K.O. Sigel |
Abstract |
The primarily function of cobalt in humans is based on its role in cobalamin (Cbl, vitamin B12). Therefore, this chapter will focus on the physiological roles of Cbl and the importance of cobalt in human health. Cbl acts as the cofactor for two enzymes, i.e., methylmalonyl-CoA mutase and methionine synthase, in humans. Both enzymes are important for health. In addition, unlike other water-soluble vitamins, there is a unique absorption, delivery, and activation system for Cbl in mammals. Therefore, this chapter will also review the literature on the Cbl transporting system, which is crucial for Cbl function. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 1 | <1% |
Unknown | 141 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 39 | 27% |
Student > Master | 15 | 11% |
Student > Ph. D. Student | 13 | 9% |
Researcher | 12 | 8% |
Student > Doctoral Student | 6 | 4% |
Other | 19 | 13% |
Unknown | 38 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Chemistry | 36 | 25% |
Biochemistry, Genetics and Molecular Biology | 17 | 12% |
Agricultural and Biological Sciences | 12 | 8% |
Medicine and Dentistry | 12 | 8% |
Engineering | 5 | 4% |
Other | 19 | 13% |
Unknown | 41 | 29% |