Chapter title |
The Study of Cell Motility by Cell Traction Force Microscopy (CTFM)
|
---|---|
Chapter number | 16 |
Book title |
Cytoskeleton Methods and Protocols
|
Published in |
Methods in molecular biology, January 2016
|
DOI | 10.1007/978-1-4939-3124-8_16 |
Pubmed ID | |
Book ISBNs |
978-1-4939-3123-1, 978-1-4939-3124-8
|
Authors |
James H.-C. Wang, Guangyi Zhao, Bin Li |
Abstract |
Migration is a vital characteristic of various cell types and enables various cellular functions during development and wound healing. Cell movement can be measured by monitoring cell traction forces, which are generated by individual cells and transmitted to the substrate below the migrant cells. This method, termed cell traction force microscopy (CTFM), has the advantage of directly measuring the "cause" (i.e., cell traction forces, CTFs) of cell movement rather than the "effect" (i.e., cell movement itself). This chapter details the methods involved in measuring cell traction forces. Several examples are also given to illustrate various applications of CTFM in cell biology research. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 13 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 3 | 23% |
Student > Ph. D. Student | 2 | 15% |
Researcher | 2 | 15% |
Student > Master | 2 | 15% |
Professor | 1 | 8% |
Other | 1 | 8% |
Unknown | 2 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Engineering | 4 | 31% |
Chemical Engineering | 1 | 8% |
Biochemistry, Genetics and Molecular Biology | 1 | 8% |
Computer Science | 1 | 8% |
Agricultural and Biological Sciences | 1 | 8% |
Other | 2 | 15% |
Unknown | 3 | 23% |