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Telomeres and Telomerase

Overview of attention for book
Cover of 'Telomeres and Telomerase'

Table of Contents

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    Book Overview
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    Chapter 1 Introduction to Telomeres and Telomerase
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    Chapter 2 Analysis of Average Telomere Length in Human Telomeric Protein Knockout Cells Generated by CRISPR/Cas9
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    Chapter 3 Telomere Length Analysis by Quantitative Fluorescent in Situ Hybridization (Q-FISH)
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    Chapter 4 Telomere Strand-Specific Length Analysis by Fluorescent In Situ Hybridization (Q-CO-FISH)
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    Chapter 5 Telomere G-Rich Overhang Length Measurement: DSN Method
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    Chapter 6 Telomere G-Overhang Length Measurement Method 2: G-Tail Telomere HPA
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    Chapter 7 Telomere Terminal G/C Strand Synthesis: Measuring Telomerase Action and C-Rich Fill-In
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    Chapter 8 Analysis of Yeast Telomerase by Primer Extension Assays
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    Chapter 9 Assessing Telomerase Activities in Mammalian Cells Using the Quantitative PCR-Based Telomeric Repeat Amplification Protocol (qTRAP)
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    Chapter 10 Telomeres and NextGen CO-FISH: Directional Genomic Hybridization (Telo-dGH™)
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    Chapter 11 Visualization of Human Telomerase Localization by Fluorescence Microscopy Techniques
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    Chapter 12 Cytogenetic Analysis of Telomere Dysfunction
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    Chapter 13 Probing the Telomere Damage Response
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    Chapter 14 Induction of Site-Specific Oxidative Damage at Telomeres by Killerred-Fused Shelretin Proteins
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    Chapter 15 Using Protein-Fragment Complementation Assays (PCA) and Peptide Arrays to Study Telomeric Protein-Protein Interactions
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    Chapter 16 In Vitro Preparation and Crystallization of Vertebrate Telomerase Subunits
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    Chapter 17 Human Telomeric G-Quadruplex Structures and G-Quadruplex-Interactive Compounds
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    Chapter 18 Analysis of Telomere-Homologous DNA with Different Conformations Using 2D Agarose Electrophoresis and In-Gel Hybridization
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    Chapter 19 Analysis of Telomere Proteins by Chromatin Immunoprecipitation (ChIP)
Attention for Chapter 19: Analysis of Telomere Proteins by Chromatin Immunoprecipitation (ChIP)
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Chapter title
Analysis of Telomere Proteins by Chromatin Immunoprecipitation (ChIP)
Chapter number 19
Book title
Telomeres and Telomerase
Published in
Methods in molecular biology, March 2017
DOI 10.1007/978-1-4939-6892-3_19
Pubmed ID
Book ISBNs
978-1-4939-6891-6, 978-1-4939-6892-3
Authors

Feng Liu, Xuyang Feng, Wenbin Ma

Editors

Zhou Songyang

Abstract

Telomere chromatin immunoprecipitation (ChIP) is an experimental method used to determine whether proteins are associated with telomere DNA inside the nuclei of cells and tissues. Telomere-associated proteins are first covalently crosslinked to telomere DNA, and then immunoprecipitated using an antibody specific for the protein of interest. This method has become one of the most indispensable tools for investigating the protein complexes that associate with telomeres.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 4 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 4 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 1 25%
Student > Doctoral Student 1 25%
Student > Master 1 25%
Unknown 1 25%
Readers by discipline Count As %
Agricultural and Biological Sciences 1 25%
Immunology and Microbiology 1 25%
Medicine and Dentistry 1 25%
Unknown 1 25%