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Mendeley readers
| Chapter title |
Oral Delivery of Tumor-Targeting Salmonella to Treat Cancer in Mice
|
|---|---|
| Chapter number | 3 |
| Book title |
Bacterial Therapy of Cancer
|
| Published in |
Methods in molecular biology, January 2016
|
| DOI | 10.1007/978-1-4939-3515-4_3 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-3513-0, 978-1-4939-3515-4
|
| Authors |
Dongping Wei, Lijun Jia |
| Abstract |
Tumor-targeting bacteria have been developed as novel anticancer agents recently. To achieve their therapeutic effects, bacteria have conventionally been injected intravenously or intraperitoneally into animals or humans. Here, we describe the oral delivery of tumor-targeting Salmonella for cancer therapy in a mouse tumor model. We detail the experimental procedures for establishing a mouse tumor model, preparing bacterial culture, mouse gavage, and detection of the tumor-targeting capability of bacteria administered orally. We also discuss technical notes and provide practical advice that will help the users of this oral delivery model. |
Mendeley readers
The data shown below were compiled from readership statistics for 1 Mendeley reader of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 1 | 100% |
| Readers by discipline | Count | As % |
|---|---|---|
| Nursing and Health Professions | 1 | 100% |