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Hemorrhagic Fever Viruses

Overview of attention for book
Cover of 'Hemorrhagic Fever Viruses'

Table of Contents

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    Book Overview
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    Chapter 1 Global Spread of Hemorrhagic Fever Viruses: Predicting Pandemics
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    Chapter 2 An Approach to the Identification and Phylogenetic Analysis of Emerging and Hemorrhagic Fever Viruses
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    Chapter 3 Preliminary Classification of Novel Hemorrhagic Fever-Causing Viruses Using Sequence-Based PAirwise Sequence Comparison (PASC) Analysis
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    Chapter 4 Epidemiological Surveillance of Viral Hemorrhagic Fevers With Emphasis on Clinical Virology
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    Chapter 5 Diagnostics for Lassa Fever: Detecting Host Antibody Responses
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    Chapter 6 Sampling Design and Mosquito Trapping for Surveillance of Arboviral Activity
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    Chapter 7 Epidemiological Surveillance of Rodent-Borne Viruses (Roboviruses)
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    Chapter 8 Entry Studies of New World Arenaviruses
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    Chapter 9 Studies of Lassa Virus Cell Entry
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    Chapter 10 A Cell-Cell Fusion Assay to Assess Arenavirus Envelope Glycoprotein Membrane-Fusion Activity
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    Chapter 11 Assays to Assess Arenaviral Glycoprotein Function
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    Chapter 12 Expression and X-Ray Structural Determination of the Nucleoprotein of Lassa Fever Virus
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    Chapter 13 Assays to Demonstrate the Roles of Arenaviral Nucleoproteins (NPs) in Viral RNA Synthesis and in Suppressing Type I Interferon
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    Chapter 14 Intracellular Detection of Viral Transcription and Replication Using RNA FISH
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    Chapter 15 Hemorrhagic Fever Virus Budding Studies
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    Chapter 16 Roles of Arenavirus Z Protein in Mediating Virion Budding, Viral Transcription-Inhibition and Interferon-Beta Suppression
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    Chapter 17 Structure–Function Assays for Crimean–Congo Hemorrhagic Fever Virus Polymerase
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    Chapter 18 Minigenome Systems for Filoviruses
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    Chapter 19 Establishment of Bisegmented and Trisegmented Reverse Genetics Systems to Generate Recombinant Pichindé Viruses
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    Chapter 20 Murine Models for Viral Hemorrhagic Fever
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    Chapter 21 Testing Experimental Therapies in a Guinea Pig Model for Hemorrhagic Fever
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    Chapter 22 A Primate Model for Viral Hemorrhagic Fever
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    Chapter 23 A Primary Human Liver Cell Culture Model for Hemorrhagic Fever Viruses
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    Chapter 24 Protocol for the Production of a Vaccine Against Argentinian Hemorrhagic Fever
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    Chapter 25 Detection of Virus-Antibody Immune Complexes in Secondary Dengue Virus Infection
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    Chapter 26 Future Approaches to DNA Vaccination Against Hemorrhagic Fever Viruses
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    Chapter 27 Identifying Restriction Factors for Hemorrhagic Fever Viruses: Dengue and Junín
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    Chapter 28 Determining the Virus Life-Cycle Stage Blocked by an Antiviral
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    Chapter 29 Retrovirus-Based Surrogate Systems for BSL-2 High-Throughput Screening of Antivirals Targeting BSL-3/4 Hemorrhagic Fever-Causing Viruses
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    Chapter 30 Protocols to Assess Coagulation Following In Vitro Infection with Hemorrhagic Fever Viruses
Attention for Chapter 4: Epidemiological Surveillance of Viral Hemorrhagic Fevers With Emphasis on Clinical Virology
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Chapter title
Epidemiological Surveillance of Viral Hemorrhagic Fevers With Emphasis on Clinical Virology
Chapter number 4
Book title
Hemorrhagic Fever Viruses
Published in
Methods in molecular biology, January 2018
DOI 10.1007/978-1-4939-6981-4_4
Pubmed ID
Book ISBNs
978-1-4939-6980-7, 978-1-4939-6981-4

Carolina Montoya-Ruiz, Juan David Rodas


This article will outline surveillance approaches for viral hemorrhagic fevers. Specific methods for surveillance of clinical samples will be emphasized. Separate articles will describe methods for surveillance of rodent-borne viruses (roboviruses) and arthropod-borne viruses (arboviruses). Since the appearance of hantaviruses and arenaviruses in the Americas, more than 30 different species in each group have been established, and therefore they have become the most frequently emerging viruses. Flaviviruses such as yellow fever and dengue viruses, although easier to recognize, are also more widely spread and therefore considered a very important public health issue, particularly for under-developed countries. On the other hand, marburgviruses and ebolaviruses, previously thought to be restricted to the African continent, have recently been shown to be more global. For many of these agents virus isolation has been a challenging task: trapping the specific vectors (mosquitoes and ticks), and reservoirs (rodents and bats), or obtaining the samples from suspected clinical human cases demands special protective gear, uncommon devices (respirators), special facilities (BSL-3 and 4), and particular skills to recognize the slow and inapparent cytopathic effects in cell culture. Alternatively, serological and molecular approaches have been very helpful in discovering and describing newly emerging viruses in many areas where the previous resources are unavailable. Unfortunately, in many cases, detailed studies have been performed only after outbreaks occur, and then active surveillance is needed to prevent viral dissemination in human populations.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 33 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 24%
Student > Master 5 15%
Student > Bachelor 5 15%
Student > Postgraduate 3 9%
Student > Doctoral Student 2 6%
Other 7 21%
Unknown 3 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 6 18%
Medicine and Dentistry 5 15%
Social Sciences 4 12%
Biochemistry, Genetics and Molecular Biology 3 9%
Veterinary Science and Veterinary Medicine 3 9%
Other 7 21%
Unknown 5 15%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 October 2017.
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Altmetric has tracked 11,888,244 research outputs across all sources so far. This one is in the 23rd percentile – i.e., 23% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,263 research outputs from this source. They receive a mean Attention Score of 2.0. This one has gotten more attention than average, scoring higher than 56% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 274,215 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them