Chapter title |
Determining the Virus Life-Cycle Stage Blocked by an Antiviral
|
---|---|
Chapter number | 28 |
Book title |
Hemorrhagic Fever Viruses
|
Published in |
Methods in molecular biology, January 2018
|
DOI | 10.1007/978-1-4939-6981-4_28 |
Pubmed ID | |
Book ISBNs |
978-1-4939-6980-7, 978-1-4939-6981-4
|
Authors |
Claudia S. Sepúlveda, Cybele C. García, Elsa B. Damonte |
Abstract |
Among the members of the Arenaviridae family, Junín virus and Lassa virus represent important human health threats generating annual outbreaks of severe human hemorrhagic fever (HF) in endemic areas of Argentina and Western Africa, respectively. Given the lack of a specific and safe chemotherapy, the search for effective antiviral compounds is a continuous demanding effort. During the last two decades, academic research studies originated important results identifying novel molecules to be considered for further in vivo characterization. This chapter summarizes experimental in vitro approaches used to determine the possible mechanism of action of these antiviral agents. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 13 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 3 | 23% |
Student > Master | 2 | 15% |
Student > Ph. D. Student | 2 | 15% |
Professor > Associate Professor | 2 | 15% |
Student > Postgraduate | 2 | 15% |
Other | 0 | 0% |
Unknown | 2 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 4 | 31% |
Environmental Science | 1 | 8% |
Nursing and Health Professions | 1 | 8% |
Immunology and Microbiology | 1 | 8% |
Social Sciences | 1 | 8% |
Other | 2 | 15% |
Unknown | 3 | 23% |