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Recombinant Glycoprotein Production

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Cover of 'Recombinant Glycoprotein Production'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Platforms for Recombinant Therapeutic Glycoprotein Production
  3. Altmetric Badge
    Chapter 2 Uncovering Innovation Features and Emerging Technologies in Molecular Biology through Patent Analysis
  4. Altmetric Badge
    Chapter 3 Production of Full-Length Antibody by Pichia pastoris
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    Chapter 4 Human Cells as Platform to Produce Gamma-Carboxylated Proteins
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    Chapter 5 Production of Recombinant Factor VIII in Human Cell Lines
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    Chapter 6 Strategies to Suspension Serum-Free Adaptation of Mammalian Cell Lines for Recombinant Glycoprotein Production
  8. Altmetric Badge
    Chapter 7 Production of Recombinant Rabies Virus Glycoprotein by Insect Cells in a Single-Use Fixed-Bed Bioreactor
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    Chapter 8 Cell-Free Production of Protein Biologics Within 24 H
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    Chapter 9 Demonstration-Scale High-Cell-Density Fermentation of Pichia pastoris
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    Chapter 10 Large-Scale Transient Transfection of Suspension Mammalian Cells for VLP Production
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    Chapter 11 Bioreactor-Based Production of Glycoproteins in Plant Cell Suspension Cultures
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    Chapter 12 Fed-Batch CHO Cell Culture for Lab-Scale Antibody Production
  14. Altmetric Badge
    Chapter 13 Strategies to Develop Therapeutic N- and O-Hyperglycosylated Proteins
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    Chapter 14 Expression of Glycosylated Proteins in Bacterial System and Purification by Affinity Chromatography
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    Chapter 15 Purification Methods for Recombinant Factor VIII Expressed in Human Liver SK-Hep Cells
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    Chapter 16 Purification Method for Recombinant hG-CSF by Affinity Chromatography
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    Chapter 17 Microplate-Based Method for High-Throughput Screening (HTS) of Chromatographic Conditions Studies for Recombinant Protein Purification
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    Chapter 18 Purification and Autoactivation Method for Recombinant Coagulation Factor VII
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    Chapter 19 Preparation of Immunoliposomes by Direct Coupling of Antibodies Based on a Thioether Bond
  21. Altmetric Badge
    Chapter 20 Polyester-Based Nanoparticles for the Encapsulation of Monoclonal Antibodies
  22. Altmetric Badge
    Chapter 21 Polyester-Based Nanoparticles for Delivery of Therapeutic Proteins
  23. Altmetric Badge
    Chapter 22 Quantification of Coagulation Factor VIII by Selective Reaction Monitoring
Attention for Chapter 1: Platforms for Recombinant Therapeutic Glycoprotein Production
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Chapter title
Platforms for Recombinant Therapeutic Glycoprotein Production
Chapter number 1
Book title
Recombinant Glycoprotein Production
Published in
Methods in molecular biology, January 2018
DOI 10.1007/978-1-4939-7312-5_1
Pubmed ID
Book ISBNs
978-1-4939-7311-8, 978-1-4939-7312-5
Authors

Amanda Mizukami, Angelo Luis Caron, Virgínia Picanço-Castro, Kamilla Swiech, Mizukami, Amanda, Caron, Angelo Luis, Picanço-Castro, Virgínia, Swiech, Kamilla

Abstract

The majority of FDA-approved biology-derived products are recombinant glycoproteins. These proteins have been used for the treatment of several diseases, with numerous products currently approved for clinical use. The choice of the expression system is a key step toward a successful functional protein production, since glycosylation influences yield, pharmacokinetics, biological activity, and immunogenicity. This chapter covers the general aspects of therapeutic recombinant glycoproteins and the platforms that are being employed for their production.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 33 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 7 21%
Student > Master 5 15%
Researcher 4 12%
Student > Ph. D. Student 3 9%
Student > Doctoral Student 2 6%
Other 3 9%
Unknown 9 27%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 10 30%
Agricultural and Biological Sciences 5 15%
Medicine and Dentistry 2 6%
Environmental Science 1 3%
Chemical Engineering 1 3%
Other 3 9%
Unknown 11 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 November 2022.
All research outputs
#20,594,080
of 23,179,757 outputs
Outputs from Methods in molecular biology
#10,041
of 13,295 outputs
Outputs of similar age
#378,915
of 443,097 outputs
Outputs of similar age from Methods in molecular biology
#1,194
of 1,499 outputs
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So far Altmetric has tracked 13,295 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 1,499 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.