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RNA Vaccines

Overview of attention for book
Cover of 'RNA Vaccines'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Introduction to RNA Vaccines.
  3. Altmetric Badge
    Chapter 2 Self-Replicating RNA.
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    Chapter 3 Self-Replicating RNA Vaccine Delivery to Dendritic Cells.
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    Chapter 4 Plant Expression of Trans-Encapsidated Viral Nanoparticle Vaccines with Animal RNA Replicons.
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    Chapter 5 RNActive® Technology: Generation and Testing of Stable and Immunogenic mRNA Vaccines.
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    Chapter 6 Nucleoside Modified mRNA Vaccines for Infectious Diseases.
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    Chapter 7 Generation and Evaluation of Prophylactic mRNA Vaccines Against Allergy.
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    Chapter 8 Measuring the Adjuvant Activity of RNA Vaccines.
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    Chapter 9 Generation of Immunostimulating 130 nm Protamine-RNA nanoparticles.
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    Chapter 10 Electroporation of mRNA as Universal Technology Platform to Transfect a Variety of Primary Cells with Antigens and Functional Proteins.
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    Chapter 11 Adjuvant-Enhanced mRNA Vaccines.
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    Chapter 12 Enhanced Delivery of DNA or RNA Vaccines by Electroporation.
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    Chapter 13 The European Regulatory Environment of RNA-Based Vaccines.
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    Chapter 14 Discovery and Subtyping of Neo-Epitope Specific T-Cell Responses for Cancer Immunotherapy: Addressing the Mutanome.
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    Chapter 15 Considerations for Producing mRNA Vaccines for Clinical Trials.
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    Chapter 16 Nonclinical Safety Testing of RNA Vaccines.
  18. Altmetric Badge
    Chapter 17 Immunotherapy of Uveal Melanoma: Vaccination Against Cancer.
Attention for Chapter 8: Measuring the Adjuvant Activity of RNA Vaccines.
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  • Good Attention Score compared to outputs of the same age and source (72nd percentile)

Mentioned by

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2 tweeters

Citations

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Readers on

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18 Mendeley
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Chapter title
Measuring the Adjuvant Activity of RNA Vaccines.
Chapter number 8
Book title
RNA Vaccines
Published in
Methods in molecular biology, January 2017
DOI 10.1007/978-1-4939-6481-9_8
Pubmed ID
Book ISBNs
978-1-4939-6479-6, 978-1-4939-6481-9
Authors

Norbert Pardi, Drew Weissman, Pardi, Norbert, Weissman, Drew

Editors

Thomas Kramps, Knut Elbers

Abstract

mRNA has recently arisen as a promising new drug class with the potential to be applied to various therapeutic modalities, including protein replacement and vaccination against cancer and infectious diseases. Numerous approaches have been pursued to develop potent mRNA vaccines, many of them have proved to be successful and have already entered human clinical trials. RNA, especially in vitro transcribed, is extremely immunogenic as it induces innate immune responses through the activation of a variety of pattern recognition receptors. This feature of RNA is potentially beneficial for vaccine development, where antigen-encoding RNA might also function as an adjuvant to elicit potent antigen-specific T and B cell immune responses. Here, we describe the methods that can be used to evaluate the immunogenicity of RNA vaccines in vitro and in vivo.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 18 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 22%
Other 3 17%
Student > Ph. D. Student 2 11%
Student > Bachelor 2 11%
Student > Master 1 6%
Other 1 6%
Unknown 5 28%
Readers by discipline Count As %
Medicine and Dentistry 2 11%
Immunology and Microbiology 2 11%
Agricultural and Biological Sciences 2 11%
Biochemistry, Genetics and Molecular Biology 1 6%
Pharmacology, Toxicology and Pharmaceutical Science 1 6%
Other 4 22%
Unknown 6 33%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 September 2021.
All research outputs
#12,947,521
of 21,963,432 outputs
Outputs from Methods in molecular biology
#3,457
of 12,584 outputs
Outputs of similar age
#208,253
of 421,568 outputs
Outputs of similar age from Methods in molecular biology
#431
of 1,652 outputs
Altmetric has tracked 21,963,432 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 12,584 research outputs from this source. They receive a mean Attention Score of 3.3. This one has gotten more attention than average, scoring higher than 70% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 421,568 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1,652 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.