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ERK Signaling

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Cover of 'ERK Signaling'

Table of Contents

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    Book Overview
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    Chapter 1 How Genetics Has Helped Piece Together the MAPK Signaling Pathway.
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    Chapter 2 In Vitro Enzyme Kinetics Analysis of EGFR.
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    Chapter 3 High-Throughput Analysis of Mammalian Receptor Tyrosine Kinase Activation in Yeast Cells.
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    Chapter 4 Structural Studies of ERK2 Protein Complexes.
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    Chapter 5 Isolation and Characterization of Intrinsically Active (MEK-Independent) Mutants of Mpk1/Erk.
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    Chapter 6 Assaying Activation and Subcellular Localization of ERK in Cells and Tissues.
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    Chapter 7 Detection and Functional Analysis of SUMO-Modified MEK.
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    Chapter 8 Single-Step Affinity Purification of ERK Signaling Complexes Using the Streptavidin-Binding Peptide (SBP) Tag.
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    Chapter 9 High-Throughput In Vitro Identification of Direct MAPK/Erk Substrates.
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    Chapter 10 Global Identification of ERK Substrates by Phosphoproteomics Based on IMAC and 2D-DIGE.
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    Chapter 11 Analysis of Ras/ERK Compartmentalization by Subcellular Fractionation.
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    Chapter 12 Cell-Based Assays to Study ERK Pathway/Caveolin1 Interactions.
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    Chapter 13 The Nuclear Translocation of ERK.
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    Chapter 14 Visualization of RAS/MAPK Signaling In Situ by the Proximity Ligation Assay (PLA).
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    Chapter 15 Measuring ERK Activity Dynamics in Single Living Cells Using FRET Biosensors.
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    Chapter 16 Quantifying Tensile Force and ERK Phosphorylation on Actin Stress Fibers.
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    Chapter 17 Co-culture Activation of MAP Kinase in Drosophila S2 Cells.
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    Chapter 18 ERK Signaling
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    Chapter 19 3D Organotypic Culture Model to Study Components of ERK Signaling.
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    Chapter 20 Genetic Validation of Cell Proliferation via Ras-Independent Activation of the Raf/Mek/Erk Pathway.
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    Chapter 21 Genome-Wide Analysis of RAS/ERK Signaling Targets.
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    Chapter 22 Probing Chromatin Modifications in Response to ERK Signaling.
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    Chapter 23 Analyzing pERK Activation During Planarian Regeneration.
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    Chapter 24 Discovering Functional ERK Substrates Regulating Caenorhabditis elegans Germline Development.
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    Chapter 25 Reconstructing ERK Signaling in the Drosophila Embryo from Fixed Images.
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    Chapter 26 Using CRISPR-Cas9 to Study ERK Signaling in Drosophila.
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    Chapter 27 Analyzing ERK Signal Dynamics During Zebrafish Somitogenesis.
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    Chapter 28 Modeling RASopathies with Genetically Modified Mouse Models.
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    Chapter 29 Dissecting Cell-Fate Determination Through Integrated Mathematical Modeling of the ERK/MAPK Signaling Pathway.
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