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Data Mining Techniques for the Life Sciences

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Cover of 'Data Mining Techniques for the Life Sciences'

Table of Contents

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    Book Overview
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    Chapter 1 Data Mining Techniques for the Life Sciences
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    Chapter 2 Protein Structure Databases.
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    Chapter 3 The MIntAct Project and Molecular Interaction Databases.
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    Chapter 4 Applications of Protein Thermodynamic Database for Understanding Protein Mutant Stability and Designing Stable Mutants.
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    Chapter 5 Classification and Exploration of 3D Protein Domain Interactions Using Kbdock.
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    Chapter 6 Data Mining of Macromolecular Structures.
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    Chapter 7 Criteria to Extract High-Quality Protein Data Bank Subsets for Structure Users.
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    Chapter 8 Homology-Based Annotation of Large Protein Datasets.
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    Chapter 9 Data Mining Techniques for the Life Sciences
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    Chapter 10 Improving the Accuracy of Fitted Atomic Models in Cryo-EM Density Maps of Protein Assemblies Using Evolutionary Information from Aligned Homologous Proteins.
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    Chapter 11 Systematic Exploration of an Efficient Amino Acid Substitution Matrix: MIQS.
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    Chapter 12 Promises and Pitfalls of High-Throughput Biological Assays.
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    Chapter 13 Data Mining Techniques for the Life Sciences
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    Chapter 14 Predicting Conformational Disorder.
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    Chapter 15 Classification of Protein Kinases Influenced by Conservation of Substrate Binding Residues.
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    Chapter 16 Spectral-Statistical Approach for Revealing Latent Regular Structures in DNA Sequence.
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    Chapter 17 Protein Crystallizability.
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    Chapter 18 Data Mining Techniques for the Life Sciences
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    Chapter 19 Data Mining Techniques for the Life Sciences
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    Chapter 20 Functional Analysis of Metabolomics Data.
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    Chapter 21 Data Mining Techniques for the Life Sciences
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    Chapter 22 A Broad Overview of Computational Methods for Predicting the Pathophysiological Effects of Non-synonymous Variants.
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    Chapter 23 Recommendation Techniques for Drug-Target Interaction Prediction and Drug Repositioning.
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    Chapter 24 Protein Residue Contacts and Prediction Methods.
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    Chapter 25 The Recipe for Protein Sequence-Based Function Prediction and Its Implementation in the ANNOTATOR Software Environment.
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    Chapter 26 Data Mining Techniques for the Life Sciences
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    Chapter 27 Data Mining Techniques for the Life Sciences
Attention for Chapter 3: The MIntAct Project and Molecular Interaction Databases.
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Citations

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Chapter title
The MIntAct Project and Molecular Interaction Databases.
Chapter number 3
Book title
Data Mining Techniques for the Life Sciences
Published in
Methods in molecular biology, January 2016
DOI 10.1007/978-1-4939-3572-7_3
Pubmed ID
Book ISBNs
978-1-4939-3570-3, 978-1-4939-3572-7
Authors

Luana Licata, Sandra Orchard

Editors

Oliviero Carugo, Frank Eisenhaber

Abstract

Molecular interaction databases collect, organize, and enable the analysis of the increasing amounts of molecular interaction data being produced and published as we move towards a more complete understanding of the interactomes of key model organisms. The organization of these data in a structured format supports analyses such as the modeling of pairwise relationships between interactors into interaction networks and is a powerful tool for understanding the complex molecular machinery of the cell. This chapter gives an overview of the principal molecular interaction databases, in particular the IMEx databases, and their curation policies, use of standardized data formats and quality control rules. Special attention is given to the MIntAct project, in which IntAct and MINT joined forces to create a single resource to improve curation and software development efforts. This is exemplified as a model for the future of molecular interaction data collation and dissemination.

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 19 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 32%
Student > Bachelor 3 16%
Student > Ph. D. Student 3 16%
Student > Master 2 11%
Lecturer 1 5%
Other 2 11%
Unknown 2 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 6 32%
Computer Science 5 26%
Biochemistry, Genetics and Molecular Biology 4 21%
Chemistry 1 5%
Medicine and Dentistry 1 5%
Other 0 0%
Unknown 2 11%