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Mendeley readers
| Chapter title |
Induction of Human Regulatory T Cells with Bacterial Superantigens
|
|---|---|
| Chapter number | 16 |
| Book title |
Superantigens
|
| Published in |
Methods in molecular biology, December 2015
|
| DOI | 10.1007/978-1-4939-3344-0_16 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-3342-6, 978-1-4939-3344-0
|
| Authors |
Stefano Caserta, Amanda L. Taylor, Nadia Terrazzini, Martin J. Llewelyn |
| Editors |
Amanda J. Brosnahan |
| Abstract |
Regulatory T cells (Tregs) that suppress the activation of immune effector cells limit immunopathology and are fast emerging as therapeutic targets for autoimmune and cancer disease. Tools enabling Treg in vitro-induction, expansion, and characterization and manipulation will help future clinical developments. In this chapter, we describe in detail how to use bacterial superantigens to induce human Tregs efficiently from peripheral blood mononuclear cells. How to assess human Treg phenotype and suppressive capacity are also described. Technical details, variations, and alternative experimental conditions are provided. |
Mendeley readers
The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 11% |
| Unknown | 8 | 89% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 3 | 33% |
| Lecturer | 1 | 11% |
| Student > Bachelor | 1 | 11% |
| Student > Doctoral Student | 1 | 11% |
| Student > Ph. D. Student | 1 | 11% |
| Other | 1 | 11% |
| Unknown | 1 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Immunology and Microbiology | 3 | 33% |
| Agricultural and Biological Sciences | 1 | 11% |
| Medicine and Dentistry | 1 | 11% |
| Neuroscience | 1 | 11% |
| Chemistry | 1 | 11% |
| Other | 0 | 0% |
| Unknown | 2 | 22% |