| Chapter title |
Lipases in Green Chemistry: Deep Eutectic Solvents (DES) as New Green Solvents
|
|---|---|
| Chapter number | 19 |
| Book title |
Lipases and Phospholipases
|
| Published in |
Methods in molecular biology, August 2018
|
| DOI | 10.1007/978-1-4939-8672-9_19 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-8671-2, 978-1-4939-8672-9
|
| Authors |
Nadia Guajardo, Pablo Domínguez de María, Guajardo, Nadia, María, Pablo Domínguez de |
| Abstract |
Deep eutectic solvents (DES) may become important alternatives as versatile, biodegradable, and cost-effective solvents for biocatalysis. Especially for reactions where substrates and products of different polarities are combined, the design of a tailored solvent that may dissolve all compounds-while being enzyme-compatible at the same time-appears to be a strong ally in sustainable chemistry. Herein it is shown that the combination of DES with "water as cosolvent" (in a range from 5% to 20% water, v/v) leads to non-conventional solvents with significantly reduced viscosity. In these media, lipases and proteases can perform synthetic reactions efficiently, and hydrolytic side reactions remain suppressed (even at 20% water, v/v). The use of these less viscous non-conventional media could also provide options for hydrolase-catalyzed synthetic reactions even in continuous fashion. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 13 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 2 | 15% |
| Student > Ph. D. Student | 1 | 8% |
| Unspecified | 1 | 8% |
| Student > Postgraduate | 1 | 8% |
| Student > Master | 1 | 8% |
| Other | 0 | 0% |
| Unknown | 7 | 54% |
| Readers by discipline | Count | As % |
|---|---|---|
| Business, Management and Accounting | 2 | 15% |
| Unspecified | 1 | 8% |
| Chemical Engineering | 1 | 8% |
| Biochemistry, Genetics and Molecular Biology | 1 | 8% |
| Chemistry | 1 | 8% |
| Other | 0 | 0% |
| Unknown | 7 | 54% |