| Chapter title |
Lipase-Catalyzed Synthesis of Fatty Acid Esters of Trisaccharides
|
|---|---|
| Chapter number | 15 |
| Book title |
Lipases and Phospholipases
|
| Published in |
Methods in molecular biology, August 2018
|
| DOI | 10.1007/978-1-4939-8672-9_15 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-8671-2, 978-1-4939-8672-9
|
| Authors |
Jose L. Gonzalez-Alfonso, Leticia Casas-Godoy, Javier Arrizon, Daniel Arrieta-Baez, Antonio O. Ballesteros, Georgina Sandoval, Francisco J. Plou, Gonzalez-Alfonso, Jose L., Casas-Godoy, Leticia, Arrizon, Javier, Arrieta-Baez, Daniel, Ballesteros, Antonio O., Sandoval, Georgina, Plou, Francisco J. |
| Abstract |
Carbohydrate fatty acid esters have a broad spectrum of applications in the food, cosmetic, and pharmaceutical industries. The enzyme-catalyzed acylation is significantly more selective than the chemical process and is carried out at milder conditions. Compared with mono- and disaccharides, the acylation of trisaccharides has been less studied. However, trisaccharide esters display notable bioactive properties, probably due to the higher hydrophilicity of the sugar head group. In this chapter, we describe the acylation of two trisaccharides, maltotriose and 1-kestose, catalyzed by different immobilized lipases, using vinyl esters as acyl donors. To illustrate the potential of such compounds, the antitumor activity of 6″-O-palmitoyl-maltotriose is shown. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 7 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 2 | 29% |
| Unspecified | 1 | 14% |
| Researcher | 1 | 14% |
| Student > Doctoral Student | 1 | 14% |
| Unknown | 2 | 29% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 2 | 29% |
| Unspecified | 1 | 14% |
| Agricultural and Biological Sciences | 1 | 14% |
| Social Sciences | 1 | 14% |
| Engineering | 1 | 14% |
| Other | 0 | 0% |
| Unknown | 1 | 14% |