You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
Mendeley readers
Chapter title |
Gene Delivery Method Using Photo-Responsive Poly(β-Amino Ester) as Vectors
|
---|---|
Chapter number | 16 |
Book title |
Non-Viral Gene Delivery Vectors
|
Published in |
Methods in molecular biology, January 2016
|
DOI | 10.1007/978-1-4939-3718-9_16 |
Pubmed ID | |
Book ISBNs |
978-1-4939-3716-5, 978-1-4939-3718-9
|
Authors |
Nan Zheng, Yang Liu, Jianjun Cheng |
Abstract |
Nonviral vectors show great potential in delivering nucleic acids (NA) into many mammalian cells to achieve efficient gene transfection. Among these, cationic polymer is one of the most widely used nonviral gene delivery vectors, forming the polymer/NA complexes for the intracellular transportation and release of the genetic materials into the target mammalian cells. Here we describe the poly(β-amino ester) (PBAE) with the photo-responsive domain built in the polymers, as a UV-light-responsive nonviral gene delivery vector to deliver and release plasmid DNA (pDNA) into HeLa cells and achieve enhanced transfection efficiency. |
Mendeley readers
The data shown below were compiled from readership statistics for 6 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 6 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 2 | 33% |
Student > Ph. D. Student | 1 | 17% |
Professor > Associate Professor | 1 | 17% |
Other | 1 | 17% |
Unknown | 1 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Chemistry | 4 | 67% |
Materials Science | 1 | 17% |
Business, Management and Accounting | 1 | 17% |