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Non-Viral Gene Delivery Vectors

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Cover of 'Non-Viral Gene Delivery Vectors'

Table of Contents

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    Book Overview
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    Chapter 1 Physical Chemical and Biomolecular Methods for the Optimization of Cationic Lipid-Based Lipoplexes In Vitro for the Gene Therapy Applications
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    Chapter 2 Non-Viral Gene Delivery Vectors
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    Chapter 3 Lipoplexes from Non-viral Cationic Vectors: DOTAP-DOPE Liposomes and Gemini Micelles
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    Chapter 4 Anionic/Zwitterionic Lipid-Based Gene Vectors of pDNA
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    Chapter 5 Elaboration and Physicochemical Characterization of Niosome-Based Nioplexes for Gene Delivery Purposes
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    Chapter 6 Quantitative Intracellular Localization of Cationic Lipid–Nucleic Acid Nanoparticles with Fluorescence Microscopy
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    Chapter 7 Targeted Delivery of Peptide-Tagged DNA Lipoplexes to Hepatocellular Carcinoma Cells
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    Chapter 8 Lipoplexes Strengthened by Anionic Polymers: Easy Preparation of Highly Effective siRNA Vectors Based on Cationic Lipids and Anionic Polymers
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    Chapter 9 Polymer Based Gene Silencing: In Vitro Delivery of SiRNA
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    Chapter 10 Polyallylamine Derivatives: Novel NonToxic Transfection Agents
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    Chapter 11 Biodegradable Three-Layered Micelles and Injectable Hydrogels
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    Chapter 12 Non-Viral Gene Delivery Vectors
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    Chapter 13 Non-Viral Gene Delivery Vectors
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    Chapter 14 Characterization and Investigation of Redox-Sensitive Liposomes for Gene Delivery
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    Chapter 15 From Artificial Amino Acids to Sequence-Defined Targeted Oligoaminoamides
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    Chapter 16 Gene Delivery Method Using Photo-Responsive Poly(β-Amino Ester) as Vectors
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    Chapter 17 Thermo-Responsive Polyplex Micelles with PEG Shells and PNIPAM Layer to Protect DNA Cores for Systemic Gene Therapy
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    Chapter 18 Application of Polyethylenimine-Grafted Silicon Nanowire Arrays for Gene Transfection
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Chapter title
Non-Viral Gene Delivery Vectors
Chapter number 13
Book title
Non-Viral Gene Delivery Vectors
Published in
Methods in molecular biology, January 2016
DOI 10.1007/978-1-4939-3718-9_13
Pubmed ID
Book ISBNs
978-1-4939-3716-5, 978-1-4939-3718-9
Authors

Huang, Xiaomeng, Zhang, Mengzi, Wang, Xinmei, Lee, L James, Lee, Robert J, Xiaomeng Huang, Mengzi Zhang, Xinmei Wang, L. James Lee, Robert J. Lee

Abstract

As nonviral nucleic acid delivery vehicles, lipid nanoparticles (LNPs) have been widely used. Here we describe the synthesis and evaluation of LNPs based on targeted anionic lipid-coated polyplexs for therapeutic delivery of microRNA (miRNA) mimics. These LNPs are particularly suited for therapeutic delivery of oligonucleotide agents to leukemia cells.

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Geographical breakdown

Country Count As %
Unknown 2 100%

Demographic breakdown

Readers by professional status Count As %
Professor > Associate Professor 1 50%
Researcher 1 50%
Readers by discipline Count As %
Veterinary Science and Veterinary Medicine 1 50%
Pharmacology, Toxicology and Pharmaceutical Science 1 50%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 July 2016.
All research outputs
#20,336,031
of 22,881,154 outputs
Outputs from Methods in molecular biology
#9,921
of 13,133 outputs
Outputs of similar age
#330,743
of 393,699 outputs
Outputs of similar age from Methods in molecular biology
#1,054
of 1,471 outputs
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