Chapter title |
Therapeutic Application of Adult Stem Cells in the Heart
|
---|---|
Chapter number | 20 |
Book title |
Adult Stem Cells
|
Published in |
Methods in molecular biology, January 2017
|
DOI | 10.1007/978-1-4939-6756-8_20 |
Pubmed ID | |
Book ISBNs |
978-1-4939-6754-4, 978-1-4939-6756-8
|
Authors |
Taylor A. Johnson, Dinender K. Singla, Johnson, Taylor A., Singla, Dinender K. |
Abstract |
Cell therapies have been explored as a potential treatment avenue to treat heart diseases, such as myocardial infarction, doxorubicin-induced cardiomyopathy, and heart failure. Embryonic and adult stem cells (ASCs) have been examined in animal and clinical settings. Unlike embryonic and induced pluripotent stem cells, ASCs do not pose a threat to form teratomas, nor do they have immune system concerns, making them ideal for therapeutic use in humans. In this review, we will investigate different characteristics and sources of adult stem cells and progenitor cells, as well as determine their efficacy in cell transplantation in experimental and clinical trials. In addition, we will propose other research avenues that may promote further understanding and use of ASCs in therapeutic designs. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 23 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 6 | 26% |
Student > Ph. D. Student | 3 | 13% |
Student > Master | 2 | 9% |
Professor | 1 | 4% |
Unspecified | 1 | 4% |
Other | 2 | 9% |
Unknown | 8 | 35% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 4 | 17% |
Medicine and Dentistry | 2 | 9% |
Arts and Humanities | 1 | 4% |
Unspecified | 1 | 4% |
Computer Science | 1 | 4% |
Other | 3 | 13% |
Unknown | 11 | 48% |