Chapter title |
Derivation of Mesenchymal Stem Cells from Embryonic Stem Cells: A Non-Variable and Inexhaustive Source of Adult Stem Cells
|
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Chapter number | 2 |
Book title |
Adult Stem Cells
|
Published in |
Methods in molecular biology, February 2017
|
DOI | 10.1007/978-1-4939-6756-8_2 |
Pubmed ID | |
Book ISBNs |
978-1-4939-6754-4, 978-1-4939-6756-8
|
Authors |
Sequiera, Glen Lester, Sareen, Niketa, El-Rub, Ejlal Abu, Dhingra, Sanjiv, Glen Lester Sequiera, Niketa Sareen, Ejlal Abu El-Rub, Sanjiv Dhingra |
Abstract |
Mesenchymal stem cells (MSCs) provide an opportunity to bring the field of regenerative medicine to realization. A lot of clinical trials are presently trying to establish their applicability in real-world scenarios. Some of the biggest challenges encountered in bringing MSCs from bench to bedside are the number of MSCs required, their procurement from various sources, and the batch-to-batch variability. This often leads to inconclusive results within and between different studies. Therefore, we have hereby proposed a simple protocol to source mesenchymal stem cells through differentiation of embryonic stem cells. |
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