Jiao, Xuanmao, Rizvanov, Albert A, Cristofanilli, Massimo, Miftakhova, Regina R, Pestell, Richard G, Xuanmao Jiao, Albert A. Rizvanov, Massimo Cristofanilli, Regina R. Miftakhova, Richard G. Pestell, Rizvanov, Albert A., Miftakhova, Regina R., Pestell, Richard G.
Abstract
Cells within the tumor are highly heterogeneous. Only a small portion of the cells within the tumor is capable to generate a new tumor. These cells are called cancer stem cells. Theoretically, cancer stem cells are originally from normal stem cells or early progenitor cells which accumulate the random mutations and undergo an altered version of the normal differentiation process. The cancer stem cell drives tumor progression and its recurrence. Thus, the technique to identify and purify the cancer stem cell is the key in any cancer stem cell research. In this protocol, we provide the basic technology of identification and purification of breast cancer stem cells as well as further functional assays to help the researchers achieve their research goals.
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 February 2016.
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#18,437,241
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Outputs from Methods in molecular biology
#7,922
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#284,431
of 393,571 outputs
Outputs of similar age from Methods in molecular biology
#846
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