Schmitt, David, Andrews, Joel, Tan, Ming, David Schmitt, Joel Andrews, Ming Tan
Abstract
Cell migration is defined as the movement of individual cells, sheets of cells, or clusters of cells from one location to another (Friedl et al., Int J Dev Biol 48:441-449, 2004). This ability of cells to migrate is critical to a wide variety of normal and pathological processes, including embryonic development, wound healing, immune responses, and cancer (Leber et al., Int J Oncol 34:881-895, 2009). Migration of tumor cells is widely thought to be an essential component of the metastatic spread of tumor cells to new sites, and inhibiting metastasis is an important therapeutic goal in cancer treatments (Horwitz and Webb, Curr Biol 13:R756-759, 2003). Therefore, the ability to observe and quantify migration in cancer cells is critical not only for basic cancer biology but especially for drug development (Friedl and Gilmour, Nat Rev Mol Cell Biol 10: 445-457, 2009). Researchers continue to develop new techniques for measuring cell migration in vitro. This chapter will discuss two techniques commonly used to study cell migration: wound healing and Boyden chamber migration assays.
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 January 2016.
All research outputs
#20,303,950
of 22,842,950 outputs
Outputs from Methods in molecular biology
#9,917
of 13,127 outputs
Outputs of similar age
#330,613
of 393,571 outputs
Outputs of similar age from Methods in molecular biology
#1,053
of 1,470 outputs
Altmetric has tracked 22,842,950 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,127 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 393,571 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1,470 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
