Chapter title |
Single Nucleotide Polymorphisms as Genomic Markers for High-Throughput Pharmacogenomic Studies.
|
---|---|
Chapter number | 11 |
Book title |
Microarray Technology
|
Published in |
Methods in molecular biology, January 2016
|
DOI | 10.1007/978-1-4939-3136-1_11 |
Pubmed ID | |
Book ISBNs |
978-1-4939-3135-4, 978-1-4939-3136-1
|
Authors |
Lonetti, Annalisa, Fontana, Maria Chiara, Martinelli, Giovanni, Iacobucci, Ilaria, Annalisa Lonetti, Maria Chiara Fontana, Giovanni Martinelli, Ilaria Iacobucci |
Abstract |
Genetic variations in patients have strong impact on their drug therapies and responses because the variations may contribute to the efficacy and/or produce undesirable side effects for any given drug. The Drug Metabolizing Enzymes and Transporters (DMET) assay is a high-throughput technology by Affymetrix that is able to simultaneously genotype variants in multiple genes involved in absorption, distribution, metabolism, and excretion of drugs for subsequent clinical applications, i.e., the assay allows for a precise genetic map that can guide therapeutic interventions and avoid side effects. |
X Demographics
Geographical breakdown
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 40 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 7 | 18% |
Student > Bachelor | 6 | 15% |
Student > Master | 6 | 15% |
Lecturer | 5 | 13% |
Other | 4 | 10% |
Other | 4 | 10% |
Unknown | 8 | 20% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 13 | 33% |
Medicine and Dentistry | 7 | 18% |
Agricultural and Biological Sciences | 6 | 15% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
Immunology and Microbiology | 1 | 3% |
Other | 3 | 8% |
Unknown | 9 | 23% |