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Viruses, Genes, and Cancer

Overview of attention for book
Cover of 'Viruses, Genes, and Cancer'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 3 Infectious Agents in Bovine Red Meat and Milk and Their Potential Role in Cancer and Other Chronic Diseases
  3. Altmetric Badge
    Chapter 4 MYC and RAF: Key Effectors in Cellular Signaling and Major Drivers in Human Cancer
  4. Altmetric Badge
    Chapter 5 The Evolution of Tumor Formation in Humans and Mice with Inherited Mutations in the p53 Gene
  5. Altmetric Badge
    Chapter 6 Oncogenic Roles of the PI3K/AKT/mTOR Axis
  6. Altmetric Badge
    Chapter 21 Exchange of Genetic Sequences Between Viruses and Hosts
  7. Altmetric Badge
    Chapter 33 Virus-Host Gene Interactions Define HIV-1 Disease Progression
  8. Altmetric Badge
    Chapter 34 MicroRNA Dysregulation to Identify Novel Therapeutic Targets
  9. Altmetric Badge
    Chapter 35 Sequencing the Biology of Entry: The Retroviral env Gene
Attention for Chapter 33: Virus-Host Gene Interactions Define HIV-1 Disease Progression
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About this Attention Score

  • Average Attention Score compared to outputs of the same age
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

twitter
2 tweeters

Citations

dimensions_citation
6 Dimensions

Readers on

mendeley
26 Mendeley
Summary Twitter Dimensions citations
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Chapter title
Virus-Host Gene Interactions Define HIV-1 Disease Progression
Chapter number 33
Book title
Current Topics in Microbiology and Immunology
Published in
Current topics in microbiology and immunology, June 2017
DOI 10.1007/82_2017_33
Pubmed ID
28653187
Book ISBNs
978-3-31-961803-6, 978-3-31-961804-3
Authors

Monaco, Daniela C., Ende, Zachary, Hunter, Eric, Daniela C. Monaco, Zachary Ende, Eric Hunter

Abstract

In this chapter, we will review recent research on the virology of HIV-1 transmission and the impact of the transmitted virus genotype on subsequent disease progression. In most instances of HIV-1 sexual transmission, a single genetic variant, or a very limited number of variants from the diverse viral quasi-species present in the transmitting partner establishes systemic infection. Transmission involves both stochastic and selective processes, such that in general a minority variant in the donor is transmitted. While there is clear evidence for selection, the biological properties that mediate transmission remain incompletely defined. Nevertheless, the genotype of the transmitted founder virus, which reflects prior exposure to and escape from host immune responses, clearly influences disease progression. Some escape mutations impact replicative capacity, while others effectively cloak the virus from the newly infected host's immune response by preventing recognition. It is the balance between the impact of escape mutations on viral fitness and susceptibility to the host immunogenetics that defines HIV-1 disease progression.

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Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 26 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 27%
Researcher 4 15%
Student > Bachelor 3 12%
Professor 2 8%
Student > Master 2 8%
Other 1 4%
Unknown 7 27%
Readers by discipline Count As %
Immunology and Microbiology 5 19%
Biochemistry, Genetics and Molecular Biology 5 19%
Agricultural and Biological Sciences 4 15%
Pharmacology, Toxicology and Pharmaceutical Science 1 4%
Nursing and Health Professions 1 4%
Other 4 15%
Unknown 6 23%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 July 2017.
All research outputs
#14,816,244
of 22,986,950 outputs
Outputs from Current topics in microbiology and immunology
#412
of 678 outputs
Outputs of similar age
#186,119
of 315,737 outputs
Outputs of similar age from Current topics in microbiology and immunology
#7
of 13 outputs
Altmetric has tracked 22,986,950 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 678 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.9. This one is in the 38th percentile – i.e., 38% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 315,737 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.

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