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Viruses, Genes, and Cancer

Overview of attention for book
Attention for Chapter 21: Exchange of Genetic Sequences Between Viruses and Hosts
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (83rd percentile)

Mentioned by

twitter
20 tweeters

Citations

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3 Dimensions

Readers on

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24 Mendeley
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Chapter title
Exchange of Genetic Sequences Between Viruses and Hosts
Chapter number 21
Book title
Viruses, Genes, and Cancer
Published in
Current topics in microbiology and immunology, May 2017
DOI 10.1007/82_2017_21
Pubmed ID
Book ISBNs
978-3-31-961803-6, 978-3-31-961804-3
Authors

Weiss, Robin A., Robin A. Weiss

Abstract

Although genetic transfer between viruses and vertebrate hosts occurs less frequently than gene flow between bacteriophages and prokaryotes, it is extensive and has affected the evolution of both parties. With retroviruses, the integration of proviral DNA into chromosomal DNA can result in the activation of adjacent host gene expression and in the transduction of host transcripts into retroviral genomes as oncogenes. Yet in contrast to lysogenic phage, there is little evidence that viral oncogenes persist in a chain of natural transmission or that retroviral transduction is a significant driver of the horizontal spread of host genes. Conversely, integration of proviruses into the host germ line has generated endogenous retroviral genomes (ERV) in all vertebrate genomes sequenced to date. Some of these genomes retain potential infectivity and upon reactivation may transmit to other host species. During mammalian evolution, sequences of retroviral origin have been repurposed to serve host functions, such as the viral envelope glycoproteins crucial to the development of the placenta. Beyond retroviruses, DNA viruses with complex genomes have acquired numerous genes of host origin which influence replication, pathogenesis and immune evasion, while host species have accumulated germline sequences of both DNA and RNA viruses. A codicil is added on lateral transmission of cancer cells between hosts and on migration of host mitochondria into cancer cells.

Twitter Demographics

The data shown below were collected from the profiles of 20 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 4%
Unknown 23 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 29%
Student > Ph. D. Student 6 25%
Student > Bachelor 3 13%
Student > Master 2 8%
Professor 1 4%
Other 0 0%
Unknown 5 21%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 8 33%
Agricultural and Biological Sciences 4 17%
Immunology and Microbiology 2 8%
Veterinary Science and Veterinary Medicine 1 4%
Social Sciences 1 4%
Other 1 4%
Unknown 7 29%

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 November 2022.
All research outputs
#2,654,093
of 22,620,502 outputs
Outputs from Current topics in microbiology and immunology
#71
of 672 outputs
Outputs of similar age
#47,538
of 290,645 outputs
Outputs of similar age from Current topics in microbiology and immunology
#1
of 1 outputs
Altmetric has tracked 22,620,502 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 672 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 290,645 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them