RT @AvrahamCooperMD: 6/ Polymerized AAT clumps together in hepatocytes, leading to histologically visible, PAS-positive inclusions. ⚡️This…
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RT @AvrahamCooperMD: 6/ Polymerized AAT clumps together in hepatocytes, leading to histologically visible, PAS-positive inclusions. ⚡️This…
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RT @AvrahamCooperMD: 6/ Polymerized AAT clumps together in hepatocytes, leading to histologically visible, PAS-positive inclusions. ⚡️This…
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6/ Polymerized AAT clumps together in hepatocytes, leading to histologically visible, PAS-positive inclusions. ⚡️This accumulation is called a "toxic gain of function", as opposed to the toxic loss of function that leads to emphysema. https://t.co/x9pUx6