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Mendeley readers
Chapter title |
Therapeutic Options in Alpha-1 Antitrypsin Deficiency: Liver Transplantation
|
---|---|
Chapter number | 26 |
Book title |
Alpha-1 Antitrypsin Deficiency
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Published in |
Methods in molecular biology, January 2017
|
DOI | 10.1007/978-1-4939-7163-3_26 |
Pubmed ID | |
Book ISBNs |
978-1-4939-7161-9, 978-1-4939-7163-3
|
Authors |
Nedim Hadzic |
Abstract |
Alpha-1 antitrypsin deficiency is the commonest genetic condition leading to liver transplantation in childhood. It remains unclear why only a minority of individuals carrying homozygous PiZ phenotype has liver disease, but also why of those only about a quarter develops end stage liver disease, requiring liver transplantation. This intervention has now become routine worldwide with 1-year patient survival rates well above 90%. As for all autosomal recessive conditions liver donation from anonymous cadaveric sources is preferred to living related parental donors, due to their presumed heterozygous state. |
Mendeley readers
The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 8 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Librarian | 1 | 13% |
Researcher | 1 | 13% |
Other | 1 | 13% |
Student > Doctoral Student | 1 | 13% |
Unknown | 4 | 50% |
Readers by discipline | Count | As % |
---|---|---|
Nursing and Health Professions | 2 | 25% |
Economics, Econometrics and Finance | 1 | 13% |
Unknown | 5 | 63% |