Chapter title |
NMR-Based Metabolomics of Oral Biofluids
|
---|---|
Chapter number | 5 |
Book title |
Oral Biology
|
Published in |
Methods in molecular biology, January 2017
|
DOI | 10.1007/978-1-4939-6685-1_5 |
Pubmed ID | |
Book ISBNs |
978-1-4939-6683-7, 978-1-4939-6685-1
|
Authors |
Horst Joachim Schirra, Pauline J. Ford |
Editors |
Gregory J. Seymour, Mary P. Cullinan, Nicholas C.K. Heng |
Abstract |
NMR-based metabolomics is an established technique for characterizing the metabolite profile of biological fluids and investigating how metabolite profiles change in response to biological and/or clinical stimuli. Thus, NMR-based metabolomics has the potential to discover biomarkers for diagnosis, prognosis, and/or therapy of clinical conditions, as well as to unravel the physiology underlying clinical conditions. Here, we describe a detailed protocol for NMR-based metabolomics of oral biofluids, including sample collection, sample handling, NMR data acquisition, and processing. In addition, we give a general overview of the statistical analysis of the resulting metabolomic data. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 9 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Unspecified | 1 | 11% |
Professor > Associate Professor | 1 | 11% |
Student > Bachelor | 1 | 11% |
Unknown | 6 | 67% |
Readers by discipline | Count | As % |
---|---|---|
Unspecified | 1 | 11% |
Chemistry | 1 | 11% |
Medicine and Dentistry | 1 | 11% |
Unknown | 6 | 67% |