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Mendeley readers
| Chapter title |
Assessing Caspase-1 Activation.
|
|---|---|
| Chapter number | 13 |
| Book title |
NLR Proteins
|
| Published in |
Methods in molecular biology, January 2016
|
| DOI | 10.1007/978-1-4939-3566-6_13 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-3564-2, 978-1-4939-3566-6
|
| Authors |
Baptiste Guey, Virginie Petrilli |
| Editors |
Francesco Di Virgilio, Pablo Pelegrín |
| Abstract |
The caspase-1 enzymatic activity plays a major role in the innate immune response as it regulates the maturation of two major proinflammatory cytokines, the interleukin-1beta (IL-1β) and IL-18. In this chapter, we describe the technique of Western blot to assess caspase-1 activation. This method provides multiple information within one experiment. It allows the detection of both unprocessed and processed caspase-1 and substrates. |
Mendeley readers
The data shown below were compiled from readership statistics for 6 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 1 | 17% |
| Unknown | 5 | 83% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 2 | 33% |
| Student > Bachelor | 1 | 17% |
| Student > Master | 1 | 17% |
| Unknown | 2 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 2 | 33% |
| Immunology and Microbiology | 1 | 17% |
| Medicine and Dentistry | 1 | 17% |
| Unknown | 2 | 33% |