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Cancer Epigenetics

Overview of attention for book
Cover of 'Cancer Epigenetics'

Table of Contents

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    Book Overview
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    Chapter 1 Epigenetic Markers of Early Tumor Development
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    Chapter 2 Epigenetics of Solid Cancer Stem Cells
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    Chapter 3 DNA Methylation and Histone Modifications in Breast Cancer
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    Chapter 4 DNA Methylation Changes in Prostate Cancer
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    Chapter 5 DNA methylation in promoter region as biomarkers in prostate cancer.
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    Chapter 6 Epigenetics of Bladder Cancer
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    Chapter 7 Epigenetics in Myeloid Malignancies
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    Chapter 8 The Epigenetics of Brain Tumors
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    Chapter 9 DNA Methylation Changes in Cervical Cancers
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    Chapter 10 Epigenetics of colon cancer.
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    Chapter 11 Promoter Methylation in Head and Neck Tumorigenesis
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    Chapter 12 Epigenome and DNA Methylation in Oral Squamous Cell Carcinoma
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    Chapter 13 Clinical Implications of Epigenetic Alterations in Human Thoracic Malignancies: Epigenetic Alterations in Lung Cancer
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    Chapter 14 The Role of MicroRNAs in the Management of Liver Cancer.
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    Chapter 15 Epigenetics in ovarian cancer.
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    Chapter 16 DNA Methylation in Pancreatic Cancer: Protocols for the Isolation of DNA and Bisulfite Modification
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    Chapter 17 Detection and analysis of DNA methylation by pyrosequencing.
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    Chapter 18 Screening for miRNA Expression Changes Using Quantitative PCR (Q-PCR).
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    Chapter 19 Genome-Wide Methylation Analysis
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    Chapter 20 Microarray for Epigenetic Changes: Gene Expression Arrays
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    Chapter 21 Detecting DNA Methylation Using the Methylated CpG Island Amplification and Microarray Technique
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    Chapter 22 Nutrigenomics: implications for breast and colon cancer prevention.
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    Chapter 23 Dietary and lifestyle factors of DNA methylation.
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    Chapter 24 Diet, epigenetics, and cancer.
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    Chapter 25 Role of Epigenetics in Cancer Health Disparities
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    Chapter 26 Multifactorial Etiology of Gastric Cancer
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    Chapter 27 Epigenetic Epidemiology for Cancer Risk: Harnessing Germline Epigenetic Variation
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    Chapter 28 Epigenetic Biomarkers in Cancer Epidemiology
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    Chapter 29 Screening for miRNA Expression Changes Using Quantitative PCR (Q-PCR)
Attention for Chapter 22: Nutrigenomics: implications for breast and colon cancer prevention.
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Chapter title
Nutrigenomics: implications for breast and colon cancer prevention.
Chapter number 22
Book title
Cancer Epigenetics
Published in
Methods in molecular biology, February 2012
DOI 10.1007/978-1-61779-612-8_22
Pubmed ID
Book ISBNs
978-1-61779-611-1, 978-1-61779-612-8

Riscuta G, Dumitrescu RG, Gabriela Riscuta, Ramona G. Dumitrescu, Riscuta, Gabriela, Dumitrescu, Ramona G.


Nutrigenomics refers to the interaction between one's diet and his/her genes. These interactions can markedly influence digestion, absorption, and the elimination of bioactive food components, as well as influence their site of actions/molecular targets. Nutrigenomics comprises nutrigenetics, epigenetics, and transcriptomics, coupled with other "omic," such as proteomics and metabolomics, that apparently account for the wide variability in cancer risk among individuals with similar dietary habits. Multiple food components including essential nutrients, phytochemical, zoochemicals, fungochemical, and bacterochemicals have been implicated in cancer risk and tumor behavior, admittedly with mixed results. Such findings suggest that not all individuals respond identically to a diet. This chapter highlights the influence of single-nucleotide polymorphism, copy number, epigenetic events, and transcriptomic homeostasis as factors influencing the response to food components and ultimately health, including cancer risk. Both breast and colorectal cancers are reviewed as examples about how nutrigenomics may influence the response to dietary intakes. As the concept that "one size fits all" comes to an end and personalized approaches surface, additional research data will be required to identify those who will benefit most from dietary change and any who might be placed at risk because of an adjustment.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 66 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 2 3%
Unknown 64 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 11 17%
Student > Bachelor 10 15%
Researcher 9 14%
Student > Ph. D. Student 8 12%
Student > Doctoral Student 4 6%
Other 9 14%
Unknown 15 23%
Readers by discipline Count As %
Agricultural and Biological Sciences 13 20%
Medicine and Dentistry 11 17%
Biochemistry, Genetics and Molecular Biology 8 12%
Nursing and Health Professions 6 9%
Pharmacology, Toxicology and Pharmaceutical Science 3 5%
Other 9 14%
Unknown 16 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 February 2012.
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Outputs from Methods in molecular biology
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Outputs of similar age
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Outputs of similar age from Methods in molecular biology
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Altmetric has tracked 22,681,577 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,039 research outputs from this source. They receive a mean Attention Score of 3.3. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 155,676 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 85 others from the same source and published within six weeks on either side of this one. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.