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Cancer Epigenetics

Overview of attention for book
Cover of 'Cancer Epigenetics'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Epigenetic Markers of Early Tumor Development
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    Chapter 2 Epigenetics of Solid Cancer Stem Cells
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    Chapter 3 DNA Methylation and Histone Modifications in Breast Cancer
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    Chapter 4 DNA Methylation Changes in Prostate Cancer
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    Chapter 5 DNA methylation in promoter region as biomarkers in prostate cancer.
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    Chapter 6 Epigenetics of Bladder Cancer
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    Chapter 7 Epigenetics in Myeloid Malignancies
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    Chapter 8 The Epigenetics of Brain Tumors
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    Chapter 9 DNA Methylation Changes in Cervical Cancers
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    Chapter 10 Epigenetics of colon cancer.
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    Chapter 11 Promoter Methylation in Head and Neck Tumorigenesis
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    Chapter 12 Epigenome and DNA Methylation in Oral Squamous Cell Carcinoma
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    Chapter 13 Clinical Implications of Epigenetic Alterations in Human Thoracic Malignancies: Epigenetic Alterations in Lung Cancer
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    Chapter 14 The Role of MicroRNAs in the Management of Liver Cancer.
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    Chapter 15 Epigenetics in ovarian cancer.
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    Chapter 16 DNA Methylation in Pancreatic Cancer: Protocols for the Isolation of DNA and Bisulfite Modification
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    Chapter 17 Detection and analysis of DNA methylation by pyrosequencing.
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    Chapter 18 Screening for miRNA Expression Changes Using Quantitative PCR (Q-PCR).
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    Chapter 19 Genome-Wide Methylation Analysis
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    Chapter 20 Microarray for Epigenetic Changes: Gene Expression Arrays
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    Chapter 21 Detecting DNA Methylation Using the Methylated CpG Island Amplification and Microarray Technique
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    Chapter 22 Nutrigenomics: implications for breast and colon cancer prevention.
  24. Altmetric Badge
    Chapter 23 Dietary and lifestyle factors of DNA methylation.
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    Chapter 24 Diet, epigenetics, and cancer.
  26. Altmetric Badge
    Chapter 25 Role of Epigenetics in Cancer Health Disparities
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    Chapter 26 Multifactorial Etiology of Gastric Cancer
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    Chapter 27 Epigenetic Epidemiology for Cancer Risk: Harnessing Germline Epigenetic Variation
  29. Altmetric Badge
    Chapter 28 Epigenetic Biomarkers in Cancer Epidemiology
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    Chapter 29 Screening for miRNA Expression Changes Using Quantitative PCR (Q-PCR)
Attention for Chapter 15: Epigenetics in ovarian cancer.
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1 tweeter

Citations

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Readers on

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40 Mendeley
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Chapter title
Epigenetics in ovarian cancer.
Chapter number 15
Book title
Cancer Epigenetics
Published in
Methods in molecular biology, February 2012
DOI 10.1007/978-1-61779-612-8_15
Pubmed ID
Book ISBNs
978-1-61779-611-1, 978-1-61779-612-8
Authors

Seeber LM, van Diest PJ, L. M. S. Seeber, P. J. van Diest, Seeber, L. M. S., Diest, P. J., Diest, P. J. van

Abstract

Ovarian cancer is the most lethal gynecological cancer. Due to few early symptoms and a lack of early detection strategies, most patients are diagnosed with advanced-stage disease. Most of these patients, although initially responsive, eventually develop drug resistance. In this chapter, epigenetic changes in ovarian cancer are described. Various epigenetic changes including CpG island methylation and histone modification have been identified in ovarian cancer. These aberrations are associated with distinct disease subtypes and present in circulating serum of ovarian cancer patients. Several epigenetic changes have shown promise for their diagnostic, prognostic, and predictive capacity but still need further validation.In contrast to DNA mutations and deletions, epigenetic modifications are potentially reversible by epigenetic therapies. Promising preclinical studies show epigenetic drugs to enhance gene re-expression and drug sensitivity in ovarian cancer cell lines and animal models.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 5%
United Kingdom 1 3%
Unknown 37 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 18%
Student > Master 7 18%
Student > Bachelor 7 18%
Researcher 6 15%
Professor 3 8%
Other 8 20%
Unknown 2 5%
Readers by discipline Count As %
Agricultural and Biological Sciences 10 25%
Medicine and Dentistry 8 20%
Biochemistry, Genetics and Molecular Biology 7 18%
Pharmacology, Toxicology and Pharmaceutical Science 3 8%
Immunology and Microbiology 3 8%
Other 5 13%
Unknown 4 10%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 June 2012.
All research outputs
#13,856,164
of 17,367,552 outputs
Outputs from Methods in molecular biology
#5,046
of 9,919 outputs
Outputs of similar age
#98,295
of 132,776 outputs
Outputs of similar age from Methods in molecular biology
#25
of 39 outputs
Altmetric has tracked 17,367,552 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 9,919 research outputs from this source. They receive a mean Attention Score of 2.7. This one is in the 31st percentile – i.e., 31% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 132,776 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 39 others from the same source and published within six weeks on either side of this one. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.