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Mutant p53 and MDM2 in Cancer

Overview of attention for book
Mutant p53 and MDM2 in Cancer
Springer Netherlands

Table of Contents

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    Book Overview
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    Chapter 1 p53 and Hereditary Cancer
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    Chapter 2 Alterations of p63 and p73 in Human Cancers.
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    Chapter 3 Cooperation of p53 Mutations with Other Oncogenic Alterations in Cancer
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    Chapter 4 p53: Its Mutations and Their Impact on Transcription.
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    Chapter 5 Transcriptional Regulation by Mutant p53 and Oncogenesis
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    Chapter 6 p53 Mutation in the Genesis of Metastasis.
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    Chapter 7 Structural Studies on Mechanisms to Activate Mutant p53
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    Chapter 8 Mutant p53 and the Response to Chemotherapy and Radiation
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    Chapter 9 Mutant p53 and MDM2 in Cancer
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    Chapter 10 Mechanisms of Mutant p53 Stabilization in Cancer
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    Chapter 11 Crosstalk Between Mdm2, p53 and HIF1-α: Distinct Responses to Oxygen Stress and Implications for Tumour Hypoxia.
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    Chapter 12 MDM2 Overexpression, Activation of Signaling Networks, and Cell Proliferation
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    Chapter 13 p53-Independent Effects of Mdm2
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    Chapter 14 Splice Variants of MDM2 in Oncogenesis.
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    Chapter 15 Mdm2 and MdmX Involvement in Human Cancer.
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    Chapter 16 Targeting p53-MDM2-MDMX Loop for Cancer Therapy.
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    Chapter 17 Involvement of p53 in the Repair of DNA Double Strand Breaks: Multifaceted Roles of p53 in Homologous Recombination Repair (HRR) and Non-Homologous End Joining (NHEJ).
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    Chapter 18 The Role of Tumor Suppressor p53 in the Antioxidant Defense and Metabolism.
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    Chapter 19 Lung Cancer Stem Cells, p53 Mutations and MDM2
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