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Chapter title |
Quantitative DNA methylation analysis for epigenotyping of colorectal cancer.
|
---|---|
Chapter number | 15 |
Book title |
Cancer Epigenetics
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Published in |
Methods in molecular biology, January 2015
|
DOI | 10.1007/978-1-4939-1804-1_15 |
Pubmed ID | |
Book ISBNs |
978-1-4939-1803-4, 978-1-4939-1804-1
|
Authors |
Atsushi Kaneda, Koichi Yagi, Kaneda, Atsushi, Yagi, Koichi |
Abstract |
Accumulation of epigenetic alteration plays important roles in tumorigenesis. Aberrant DNA hypermethylation in gene promoter regions is a common epigenetic mechanism for silencing tumor suppressor genes in many types of cancer including colorectal cancer (CRC). By using quantitative methylation information, CRC can be classified into three distinct methylation epigenotypes with different genetic features, suggesting existence of at least three molecular pathways in genesis of CRC. We describe in this chapter, the methods for analyses of aberrant DNA methylation to epigenotype CRC. |
X Demographics
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Geographical breakdown
Country | Count | As % |
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France | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 November 2014.
All research outputs
#20,243,777
of 22,771,140 outputs
Outputs from Methods in molecular biology
#9,862
of 13,090 outputs
Outputs of similar age
#295,628
of 352,911 outputs
Outputs of similar age from Methods in molecular biology
#635
of 996 outputs
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So far Altmetric has tracked 13,090 research outputs from this source. They receive a mean Attention Score of 3.3. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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