Cancer Epigenetics
Springer New York
Chapter title |
Epigenetics of gastric cancer.
|
---|---|
Chapter number | 41 |
Book title |
Cancer Epigenetics
|
Published in |
Methods in molecular biology, January 2015
|
DOI | 10.1007/978-1-4939-1804-1_41 |
Pubmed ID | |
Book ISBNs |
978-1-4939-1803-4, 978-1-4939-1804-1
|
Authors |
Mingzhou Guo, Wenji Yan, Guo, Mingzhou, Yan, Wenji |
Abstract |
Epigenetic changes frequently occur in human gastric cancer. Gene promoter region hypermethylation, genomic global hypomethylation, histone modifications, and alterations of noncoding RNAs are major epigenetic changes in gastric cancer. As a key risk factor of gastric cancer, H. pylori infection is an independent predictive indicator of gene methylation. A growing number of epigenetic studies in gastric cancer have provided lots of potential diagnostic and prognostic markers and therapeutic targets. |
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Researcher | 2 | 13% |
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