Chapter title |
Epigenetic regulation in biopsychosocial pathways.
|
---|---|
Chapter number | 29 |
Book title |
Cancer Epigenetics
|
Published in |
Methods in molecular biology, January 2015
|
DOI | 10.1007/978-1-4939-1804-1_29 |
Pubmed ID | |
Book ISBNs |
978-1-4939-1803-4, 978-1-4939-1804-1
|
Authors |
Kristin Litzelman, Mukesh Verma, Litzelman, Kristin, Verma, Mukesh |
Abstract |
Theory and empirical evidence suggest that psychological stress and other adverse psychosocial experiences can contribute to cancer progression. Research has begun to explore the potential role of epigenetic changes in these pathways. In basic, animal and human models, exposure to stressors or to the products of the physiological stress response (e.g., cortisol) has been associated with epigenetic changes, such as DNA methylation and microRNA (miR) expression, which may influence tumor growth, progression, metastasis, or chemoresistance. However, the specific biological pathways linking stress, epigenetic changes, and cancer outcomes remain unclear. Numerous opportunities exist to extend the preliminary evidence for the role of epigenetic mechanisms in the biopsychosocial pathways contributing to cancer progression. Such work will improve our understanding of how the psychosocial environment influences cancer risk and survival, potentially leading to improved prevention and treatment strategies. |
X Demographics
Geographical breakdown
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France | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 22 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 4 | 18% |
Student > Ph. D. Student | 4 | 18% |
Student > Master | 2 | 9% |
Student > Postgraduate | 2 | 9% |
Researcher | 2 | 9% |
Other | 2 | 9% |
Unknown | 6 | 27% |
Readers by discipline | Count | As % |
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Psychology | 6 | 27% |
Medicine and Dentistry | 4 | 18% |
Nursing and Health Professions | 2 | 9% |
Social Sciences | 1 | 5% |
Neuroscience | 1 | 5% |
Other | 0 | 0% |
Unknown | 8 | 36% |