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Cancer Epigenetics

Overview of attention for book
Cover of 'Cancer Epigenetics'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Cancer epigenetics: an introduction.
  3. Altmetric Badge
    Chapter 2 Community Resources and Technologies Developed Through the NIH Roadmap Epigenomics Program.
  4. Altmetric Badge
    Chapter 3 Epigenome-Wide Association Studies (EWAS): Past, Present, and Future
  5. Altmetric Badge
    Chapter 4 Epigenetic biomarkers in liver cancer.
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    Chapter 5 Cancer type-specific epigenetic changes: gastric cancer.
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    Chapter 6 Beyond the island: epigenetic biomarkers of colorectal and prostate cancer.
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    Chapter 7 Prostate cancer epigenome.
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    Chapter 8 CpG island hypermethylation as a biomarker for the early detection of lung cancer.
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    Chapter 9 Analysis of DNA methylation in pancreatic cancer: an update.
  11. Altmetric Badge
    Chapter 10 Cancer Epigenetics
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    Chapter 11 Epigenetics of prostate cancer.
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    Chapter 12 Methylation profile landscape in mesothelioma: possible implications in early detection, disease progression, and therapeutic options.
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    Chapter 13 Techniques to access histone modifications and variants in cancer.
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    Chapter 14 Single Base Resolution Analysis of 5-Methylcytosine and 5-Hydroxymethylcytosine by RRBS and TAB-RRBS
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    Chapter 15 Quantitative DNA methylation analysis for epigenotyping of colorectal cancer.
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    Chapter 16 Histone modifications associated with cancer cell migration and invasion.
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    Chapter 17 Aberrant epigenetic modifications in radiation-resistant head and neck cancers.
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    Chapter 18 Cancer-associated infectious agents and epigenetic regulation.
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    Chapter 19 Toxicoepigenomics and cancer: implications for screening.
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    Chapter 20 Human Papilloma Virus (HPV) Modulation of the HNSCC Epigenome.
  22. Altmetric Badge
    Chapter 21 Epigenetic Regulation of HIV, AIDS, and AIDS-Related Malignancies.
  23. Altmetric Badge
    Chapter 22 Epigenetics of colorectal cancer.
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    Chapter 23 Epigenetics in breast and prostate cancer.
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    Chapter 24 Epigenetic inhibitors.
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    Chapter 25 Use of epigenetic modulators as a powerful adjuvant for breast cancer therapies.
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    Chapter 26 Epigenetic approaches in glioblastoma multiforme and their implication in screening and diagnosis.
  28. Altmetric Badge
    Chapter 27 Detection of Circulatory MicroRNAs in Prostate Cancer.
  29. Altmetric Badge
    Chapter 28 Identification and characterization of small-molecule inhibitors of lysine acetyltransferases.
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    Chapter 29 Epigenetic regulation in biopsychosocial pathways.
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    Chapter 30 Viral epigenetics.
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    Chapter 31 P53 tumor suppression network in cancer epigenetics.
  33. Altmetric Badge
    Chapter 32 Promoter Hypermethylation as a Biomarker in Prostate Adenocarcinoma
  34. Altmetric Badge
    Chapter 33 Sequencing the cancer methylome.
  35. Altmetric Badge
    Chapter 34 Global DNA methylation profiling technologies and the ovarian cancer methylome.
  36. Altmetric Badge
    Chapter 35 Recent progress in the discovery of epigenetic inhibitors for the treatment of cancer.
  37. Altmetric Badge
    Chapter 36 At the Crossroad Between Obesity and Gastric Cancer
  38. Altmetric Badge
    Chapter 37 Detection of epigenetic aberrations in the development of hepatocellular carcinoma.
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    Chapter 38 Specific type epigenetic changes in cervical cancers.
  40. Altmetric Badge
    Chapter 39 Epigenetics in head and neck cancer.
  41. Altmetric Badge
    Chapter 40 Epigenetic therapy for colorectal cancer.
  42. Altmetric Badge
    Chapter 41 Epigenetics of gastric cancer.
Attention for Chapter 11: Epigenetics of prostate cancer.
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Chapter title
Epigenetics of prostate cancer.
Chapter number 11
Book title
Cancer Epigenetics
Published in
Methods in molecular biology, January 2015
DOI 10.1007/978-1-4939-1804-1_11
Pubmed ID
Book ISBNs
978-1-4939-1803-4, 978-1-4939-1804-1
Authors

Tawnya C McKee, James V Tricoli, Tawnya C. McKee, James V. Tricoli, McKee, Tawnya C., Tricoli, James V.

Abstract

The introduction of novel technologies that can be applied to the investigation of the molecular underpinnings of human cancer has allowed for new insights into the mechanisms associated with tumor development and progression. They have also advanced the diagnosis, prognosis and treatment of cancer. These technologies include microarray and other analysis methods for the generation of large-scale gene expression data on both mRNA and miRNA, next-generation DNA sequencing technologies utilizing a number of platforms to perform whole genome, whole exome, or targeted DNA sequencing to determine somatic mutational differences and gene rearrangements, and a variety of proteomic analysis platforms including liquid chromatography/mass spectrometry (LC/MS) analysis to survey alterations in protein profiles in tumors. One other important advancement has been our current ability to survey the methylome of human tumors in a comprehensive fashion through the use of sequence-based and array-based methylation analysis (Bock et al., Nat Biotechnol 28:1106-1114, 2010; Harris et al., Nat Biotechnol 28:1097-1105, 2010). The focus of this chapter is to present and discuss the evidence for key genes involved in prostate tumor development, progression, or resistance to therapy that are regulated by methylation-induced silencing.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 1 4%
Unknown 26 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 22%
Researcher 5 19%
Student > Bachelor 4 15%
Professor > Associate Professor 3 11%
Student > Master 3 11%
Other 3 11%
Unknown 3 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 8 30%
Medicine and Dentistry 7 26%
Biochemistry, Genetics and Molecular Biology 4 15%
Chemistry 2 7%
Physics and Astronomy 1 4%
Other 1 4%
Unknown 4 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 July 2015.
All research outputs
#18,384,336
of 22,771,140 outputs
Outputs from Methods in molecular biology
#7,867
of 13,090 outputs
Outputs of similar age
#255,662
of 352,911 outputs
Outputs of similar age from Methods in molecular biology
#479
of 996 outputs
Altmetric has tracked 22,771,140 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,090 research outputs from this source. They receive a mean Attention Score of 3.3. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 352,911 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 996 others from the same source and published within six weeks on either side of this one. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.