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Cancer Epigenetics

Overview of attention for book
Cover of 'Cancer Epigenetics'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Cancer epigenetics: an introduction.
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    Chapter 2 Community Resources and Technologies Developed Through the NIH Roadmap Epigenomics Program.
  4. Altmetric Badge
    Chapter 3 Epigenome-Wide Association Studies (EWAS): Past, Present, and Future
  5. Altmetric Badge
    Chapter 4 Epigenetic biomarkers in liver cancer.
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    Chapter 5 Cancer type-specific epigenetic changes: gastric cancer.
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    Chapter 6 Beyond the island: epigenetic biomarkers of colorectal and prostate cancer.
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    Chapter 7 Prostate cancer epigenome.
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    Chapter 8 CpG island hypermethylation as a biomarker for the early detection of lung cancer.
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    Chapter 9 Analysis of DNA methylation in pancreatic cancer: an update.
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    Chapter 10 Cancer Epigenetics
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    Chapter 11 Epigenetics of prostate cancer.
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    Chapter 12 Methylation profile landscape in mesothelioma: possible implications in early detection, disease progression, and therapeutic options.
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    Chapter 13 Techniques to access histone modifications and variants in cancer.
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    Chapter 14 Single Base Resolution Analysis of 5-Methylcytosine and 5-Hydroxymethylcytosine by RRBS and TAB-RRBS
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    Chapter 15 Quantitative DNA methylation analysis for epigenotyping of colorectal cancer.
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    Chapter 16 Histone modifications associated with cancer cell migration and invasion.
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    Chapter 17 Aberrant epigenetic modifications in radiation-resistant head and neck cancers.
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    Chapter 18 Cancer-associated infectious agents and epigenetic regulation.
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    Chapter 19 Toxicoepigenomics and cancer: implications for screening.
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    Chapter 20 Human Papilloma Virus (HPV) Modulation of the HNSCC Epigenome.
  22. Altmetric Badge
    Chapter 21 Epigenetic Regulation of HIV, AIDS, and AIDS-Related Malignancies.
  23. Altmetric Badge
    Chapter 22 Epigenetics of colorectal cancer.
  24. Altmetric Badge
    Chapter 23 Epigenetics in breast and prostate cancer.
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    Chapter 24 Epigenetic inhibitors.
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    Chapter 25 Use of epigenetic modulators as a powerful adjuvant for breast cancer therapies.
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    Chapter 26 Epigenetic approaches in glioblastoma multiforme and their implication in screening and diagnosis.
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    Chapter 27 Detection of Circulatory MicroRNAs in Prostate Cancer.
  29. Altmetric Badge
    Chapter 28 Identification and characterization of small-molecule inhibitors of lysine acetyltransferases.
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    Chapter 29 Epigenetic regulation in biopsychosocial pathways.
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    Chapter 30 Viral epigenetics.
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    Chapter 31 P53 tumor suppression network in cancer epigenetics.
  33. Altmetric Badge
    Chapter 32 Promoter Hypermethylation as a Biomarker in Prostate Adenocarcinoma
  34. Altmetric Badge
    Chapter 33 Sequencing the cancer methylome.
  35. Altmetric Badge
    Chapter 34 Global DNA methylation profiling technologies and the ovarian cancer methylome.
  36. Altmetric Badge
    Chapter 35 Recent progress in the discovery of epigenetic inhibitors for the treatment of cancer.
  37. Altmetric Badge
    Chapter 36 At the Crossroad Between Obesity and Gastric Cancer
  38. Altmetric Badge
    Chapter 37 Detection of epigenetic aberrations in the development of hepatocellular carcinoma.
  39. Altmetric Badge
    Chapter 38 Specific type epigenetic changes in cervical cancers.
  40. Altmetric Badge
    Chapter 39 Epigenetics in head and neck cancer.
  41. Altmetric Badge
    Chapter 40 Epigenetic therapy for colorectal cancer.
  42. Altmetric Badge
    Chapter 41 Epigenetics of gastric cancer.
Attention for Chapter 23: Epigenetics in breast and prostate cancer.
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (70th percentile)
  • High Attention Score compared to outputs of the same age and source (83rd percentile)

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Chapter title
Epigenetics in breast and prostate cancer.
Chapter number 23
Book title
Cancer Epigenetics
Published in
Methods in molecular biology, January 2015
DOI 10.1007/978-1-4939-1804-1_23
Pubmed ID
Book ISBNs
978-1-4939-1803-4, 978-1-4939-1804-1
Authors

Yanyuan Wu, Marianna Sarkissyan, Jaydutt V Vadgama, Wu Y, Sarkissyan M, Vadgama JV, Jaydutt V. Vadgama, Wu, Yanyuan, Sarkissyan, Marianna, Vadgama, Jaydutt V.

Abstract

Most recent investigations into cancer etiology have identified a key role played by epigenetics. Specifically, aberrant DNA and histone modifications which silence tumor suppressor genes or promote oncogenes have been demonstrated in multiple cancer models. While the role of epigenetics in several solid tumor cancers such as colorectal cancer are well established, there is emerging evidence that epigenetics also plays a critical role in breast and prostate cancer. In breast cancer, DNA methylation profiles have been linked to hormone receptor status and tumor progression. Similarly in prostate cancer, epigenetic patterns have been associated with androgen receptor status and response to therapy. The regulation of key receptor pathways and activities which affect clinical therapy treatment options by epigenetics renders this field high priority for elucidating mechanisms and potential targets. A new set of methylation arrays are now available to screen epigenetic changes and provide the cutting-edge tools needed to perform such investigations. The role of nutritional interventions affecting epigenetic changes particularly holds promise. Ultimately, determining the causes and outcomes from epigenetic changes will inform translational applications for utilization as biomarkers for risk and prognosis as well as candidates for therapy.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 145 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 145 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 23 16%
Student > Bachelor 22 15%
Researcher 17 12%
Student > Ph. D. Student 14 10%
Student > Doctoral Student 9 6%
Other 15 10%
Unknown 45 31%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 38 26%
Medicine and Dentistry 27 19%
Nursing and Health Professions 8 6%
Agricultural and Biological Sciences 5 3%
Pharmacology, Toxicology and Pharmaceutical Science 3 2%
Other 14 10%
Unknown 50 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 September 2018.
All research outputs
#7,204,207
of 22,771,140 outputs
Outputs from Methods in molecular biology
#2,192
of 13,090 outputs
Outputs of similar age
#100,464
of 352,911 outputs
Outputs of similar age from Methods in molecular biology
#158
of 996 outputs
Altmetric has tracked 22,771,140 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 13,090 research outputs from this source. They receive a mean Attention Score of 3.3. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 352,911 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 996 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.