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Pulmonary Vasculature Redox Signaling in Health and Disease

Overview of attention for book
Cover of 'Pulmonary Vasculature Redox Signaling in Health and Disease'

Table of Contents

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    Book Overview
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    Chapter 1 Adventitial Fibroblast Nox4 Expression and ROS Signaling in Pulmonary Arterial Hypertension
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    Chapter 2 Role of Transcription Factors in Pulmonary Artery Smooth Muscle Cells: An Important Link to Hypoxic Pulmonary Hypertension
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    Chapter 3 Molecular Basis of Nitrative Stress in the Pathogenesis of Pulmonary Hypertension
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    Chapter 4 Pentose Shunt, Glucose-6-Phosphate Dehydrogenase, NADPH Redox, and Stem Cells in Pulmonary Hypertension
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    Chapter 5 Redox Regulation of the Superoxide Dismutases SOD3 and SOD2 in the Pulmonary Circulation
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    Chapter 6 A Brief Overview of Nitric Oxide and Reactive Oxygen Species Signaling in Hypoxia-Induced Pulmonary Hypertension
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    Chapter 7 Altered Redox Balance in the Development of Chronic Hypoxia-induced Pulmonary Hypertension
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    Chapter 8 ROS Signaling in the Pathogenesis of Acute Lung Injury (ALI) and Acute Respiratory Distress Syndrome (ARDS)
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    Chapter 9 Redox-Dependent Calpain Signaling in Airway and Pulmonary Vascular Remodeling in COPD
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    Chapter 10 Natural Antioxidants as Potential Therapy, and a Promising Role for Melatonin Against Pulmonary Hypertension
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    Chapter 11 Effects of Hyperoxia on the Developing Airway and Pulmonary Vasculature
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    Chapter 12 Lung Ischaemia–Reperfusion Injury: The Role of Reactive Oxygen Species
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    Chapter 13 Redox Mechanisms Influencing cGMP Signaling in Pulmonary Vascular Physiology and Pathophysiology
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    Chapter 14 Metabolic Reprogramming and Redox Signaling in Pulmonary Hypertension
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    Chapter 15 Hydrogen Sulfide as an O 2 Sensor: A Critical Analysis
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    Chapter 16 Redox Signaling and Persistent Pulmonary Hypertension of the Newborn
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    Chapter 17 Cross Talk Between Mitochondrial Reactive Oxygen Species and Sarcoplasmic Reticulum Calcium in Pulmonary Arterial Smooth Muscle Cells
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    Chapter 18 Endothelial Cell Reactive Oxygen Species and Ca2+ Signaling in Pulmonary Hypertension
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    Chapter 19 Redox Signaling in the Right Ventricle
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    Chapter 20 Hypoxia and Local Inflammation in Pulmonary Artery Structure and Function
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    Chapter 21 From Physiological Redox Signalling to Oxidant Stress
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    Chapter 22 Emerging Role of MicroRNAs and Long Noncoding RNAs in Healthy and Diseased Lung
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    Chapter 23 Techniques for Detecting Reactive Oxygen Species in Pulmonary Vasculature Redox Signaling
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    Chapter 24 Mitochondrial and Metabolic Drivers of Pulmonary Vascular Endothelial Dysfunction in Pulmonary Hypertension
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    Chapter 25 Subcellular Redox Signaling
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    Chapter 26 Reactive Oxygen Species in COPD-Related Vascular Remodeling
Attention for Chapter 22: Emerging Role of MicroRNAs and Long Noncoding RNAs in Healthy and Diseased Lung
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Chapter title
Emerging Role of MicroRNAs and Long Noncoding RNAs in Healthy and Diseased Lung
Chapter number 22
Book title
Pulmonary Vasculature Redox Signaling in Health and Disease
Published in
Advances in experimental medicine and biology, January 2017
DOI 10.1007/978-3-319-63245-2_22
Pubmed ID
29047098
Book ISBNs
978-3-31-963244-5, 978-3-31-963245-2
Authors

Jun-Hua Xiao, Qiong-Yu Hao, Katie Wang, Jes Paul, Yong-Xiao Wang, Xiao, Jun-Hua, Hao, Qiong-Yu, Wang, Katie, Paul, Jes, Wang, Yong-Xiao

Abstract

Pulmonary hypertension (PH) is a complex and multifactorial disease. An inability to fully unravel the molecular complexities has led to various clinical challenges in developing new therapies for this disease. Noncoding RNAs (ncRNAs) are RNA molecules with limited ability of coding proteins. The amount of ncRNAs is up to 98% of the whole genome's transcripts. Many ncRNAs with a regulatory function of genes have been identified to date and found to act at various steps along the protein biosynthetic process, which includes transcription, RNA maturation, translation, and protein degradation. These discoveries are fueling a new era in understanding the pathophysiology and therapeutic pathways of PH. In this chapter, we discuss the emerging role of noncoding RNAs in PH as well as other pulmonary diseases.

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
 Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 9 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 44%
Student > Bachelor 1 11%
Unknown 4 44%
Readers by discipline Count As %
Nursing and Health Professions 2 22%
Agricultural and Biological Sciences 2 22%
Medicine and Dentistry 1 11%
Chemistry 1 11%
Unknown 3 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 October 2017.
All research outputs
#14,957,541
of 23,006,268 outputs
Outputs from Advances in experimental medicine and biology
#2,272
of 4,961 outputs
Outputs of similar age
#243,427
of 421,241 outputs
Outputs of similar age from Advances in experimental medicine and biology
#209
of 490 outputs
Altmetric has tracked 23,006,268 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,961 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.1. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 421,241 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 490 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.

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