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Yeast Membrane Transport

Overview of attention for book
Attention for Chapter 14: Antifungals: Mechanism of Action and Drug Resistance
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (72nd percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

Mentioned by

twitter
3 tweeters
wikipedia
1 Wikipedia page

Citations

dimensions_citation
17 Dimensions

Readers on

mendeley
201 Mendeley
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Chapter title
Antifungals: Mechanism of Action and Drug Resistance
Chapter number 14
Book title
Yeast Membrane Transport
Published in
Advances in experimental medicine and biology, February 2016
DOI 10.1007/978-3-319-25304-6_14
Pubmed ID
Book ISBNs
978-3-31-925302-2, 978-3-31-925304-6
Authors

Rajendra Prasad, Abdul Haseeb Shah, Manpreet Kaur Rawal, Prasad, Rajendra, Shah, Abdul Haseeb, Rawal, Manpreet Kaur

Abstract

There are currently few antifungals in use which show efficacy against fungal diseases. These antifungals mostly target specific components of fungal plasma membrane or its biosynthetic pathways. However, more recent class of antifungals in use is echinocandins which target the fungal cell wall components. The availability of mostly fungistatic antifungals in clinical use, often led to the development of tolerance to these very drugs by the pathogenic fungal species. Thus, the development of clinical multidrug resistance (MDR) leads to higher tolerance to drugs and its emergence is helped by multiple mechanisms. MDR is indeed a multifactorial phenomenon wherein a resistant organism possesses several mechanisms which contribute to display reduced susceptibility to not only single drug in use but also show collateral resistance to several drugs. Considering the limited availability of antifungals in use and the emergence of MDR in fungal infections, there is a continuous need for the development of novel broad spectrum antifungal drugs with better efficacy. Here, we briefly present an overview of the current understanding of the antifungal drugs in use, their mechanism of action and the emerging possible novel antifungal drugs with great promise.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 201 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 <1%
Unknown 200 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 42 21%
Student > Master 22 11%
Student > Ph. D. Student 21 10%
Student > Postgraduate 13 6%
Researcher 12 6%
Other 33 16%
Unknown 58 29%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 29 14%
Pharmacology, Toxicology and Pharmaceutical Science 25 12%
Immunology and Microbiology 20 10%
Agricultural and Biological Sciences 19 9%
Medicine and Dentistry 18 9%
Other 26 13%
Unknown 64 32%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 June 2022.
All research outputs
#6,171,002
of 22,029,478 outputs
Outputs from Advances in experimental medicine and biology
#951
of 4,791 outputs
Outputs of similar age
#101,695
of 378,134 outputs
Outputs of similar age from Advances in experimental medicine and biology
#131
of 693 outputs
Altmetric has tracked 22,029,478 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 4,791 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.9. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 378,134 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 693 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.