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Retinal Gene Therapy

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Cover of 'Retinal Gene Therapy'

Table of Contents

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    Book Overview
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    Chapter 1 Small Scale Production of Recombinant Adeno-Associated Viral Vectors for Gene Delivery to the Nervous System
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    Chapter 2 Small and Micro-Scale Recombinant Adeno-Associated Virus Production and Purification for Ocular Gene Therapy Applications
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    Chapter 3 Design and Development of AAV-based Gene Supplementation Therapies for Achromatopsia and Retinitis Pigmentosa
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    Chapter 4 Development of Multigenic Lentiviral Vectors for Cell-Specific Expression of Antiangiogenic miRNAs and Protein Factors
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    Chapter 5 Design and In Vitro Use of Antisense Oligonucleotides to Correct Pre-mRNA Splicing Defects in Inherited Retinal Dystrophies
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    Chapter 6 Three-Dimensional Co-Culture Bioassay for Screening of Retinal Gene Delivery Systems
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    Chapter 7 Retinal Gene Therapy for Choroideremia: In Vitro Testing for Gene Augmentation Using an Adeno-Associated Viral (AAV) Vector
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    Chapter 8 In Vivo Electroporation of Developing Mouse Retina
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    Chapter 9 Methods for In Vivo CRISPR/Cas Editing of the Adult Murine Retina
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    Chapter 10 AAV Gene Augmentation Therapy for CRB1-Associated Retinitis Pigmentosa
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    Chapter 11 Dual AAV Vectors for Stargardt Disease
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    Chapter 12 Optogenetic Retinal Gene Therapy with the Light Gated GPCR Vertebrate Rhodopsin
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    Chapter 13 CRISPR Repair Reveals Causative Mutation in a Preclinical Model of Retinitis Pigmentosa: A Brief Methodology
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    Chapter 14 In-Depth Functional Analysis of Rodents by Full-Field Electroretinography
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    Chapter 15 Advanced Ocular Injection Techniques for Therapy Approaches
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    Chapter 16 Neutralizing Antibodies Against Adeno-Associated Virus (AAV): Measurement and Influence on Retinal Gene Delivery
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    Chapter 17 Screening for Neutralizing Antibodies Against Natural and Engineered AAV Capsids in Nonhuman Primate Retinas
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    Chapter 18 Subretinal and Intravitreal Retinal Injections in Monkeys
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    Chapter 19 Production of iPS-Derived Human Retinal Organoids for Use in Transgene Expression Assays
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    Chapter 20 AAV Serotype Testing on Cultured Human Donor Retinal Explants
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    Chapter 21 Human Retinal Explant Culture for Ex Vivo Validation of AAV Gene Therapy
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    Chapter 22 Visual Acuity Testing Before and After Intravitreal Injection of rAAV2-ND4 in Patients
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    Chapter 23 Recording and Analysis of the Human Clinical Electroretinogram
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    Chapter 24 Recording and Analysis of Goldmann Kinetic Visual Fields
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    Chapter 25 Measuring Central Retinal Sensitivity Using Microperimetry
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    Chapter 26 Inspection of the Human Retina by Optical Coherence Tomography
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    Chapter 27 Vector Shedding and Immunogenicity Sampling for Retinal Gene Therapy
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Title
Retinal Gene Therapy
Published by
Humana Press, New York, NY, December 2017
DOI 10.1007/978-1-4939-7522-8
ISBNs
978-1-4939-7521-1, 978-1-4939-7522-8
Editors

Camiel J.F. Boon, Jan Wijnholds

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X Demographics

The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 5 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 5 100%

Demographic breakdown

Readers by professional status Count As %
Other 2 40%
Researcher 1 20%
Student > Master 1 20%
Unknown 1 20%
Readers by discipline Count As %
Engineering 2 40%
Medicine and Dentistry 1 20%
Immunology and Microbiology 1 20%
Unknown 1 20%