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Pulmonary Vasculature Redox Signaling in Health and Disease

Overview of attention for book
Cover of 'Pulmonary Vasculature Redox Signaling in Health and Disease'

Table of Contents

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    Book Overview
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    Chapter 1 Adventitial Fibroblast Nox4 Expression and ROS Signaling in Pulmonary Arterial Hypertension
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    Chapter 2 Role of Transcription Factors in Pulmonary Artery Smooth Muscle Cells: An Important Link to Hypoxic Pulmonary Hypertension
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    Chapter 3 Molecular Basis of Nitrative Stress in the Pathogenesis of Pulmonary Hypertension
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    Chapter 4 Pentose Shunt, Glucose-6-Phosphate Dehydrogenase, NADPH Redox, and Stem Cells in Pulmonary Hypertension
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    Chapter 5 Redox Regulation of the Superoxide Dismutases SOD3 and SOD2 in the Pulmonary Circulation
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    Chapter 6 A Brief Overview of Nitric Oxide and Reactive Oxygen Species Signaling in Hypoxia-Induced Pulmonary Hypertension
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    Chapter 7 Altered Redox Balance in the Development of Chronic Hypoxia-induced Pulmonary Hypertension
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    Chapter 8 ROS Signaling in the Pathogenesis of Acute Lung Injury (ALI) and Acute Respiratory Distress Syndrome (ARDS)
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    Chapter 9 Redox-Dependent Calpain Signaling in Airway and Pulmonary Vascular Remodeling in COPD
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    Chapter 10 Natural Antioxidants as Potential Therapy, and a Promising Role for Melatonin Against Pulmonary Hypertension
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    Chapter 11 Effects of Hyperoxia on the Developing Airway and Pulmonary Vasculature
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    Chapter 12 Lung Ischaemia–Reperfusion Injury: The Role of Reactive Oxygen Species
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    Chapter 13 Redox Mechanisms Influencing cGMP Signaling in Pulmonary Vascular Physiology and Pathophysiology
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    Chapter 14 Metabolic Reprogramming and Redox Signaling in Pulmonary Hypertension
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    Chapter 15 Hydrogen Sulfide as an O 2 Sensor: A Critical Analysis
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    Chapter 16 Redox Signaling and Persistent Pulmonary Hypertension of the Newborn
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    Chapter 17 Cross Talk Between Mitochondrial Reactive Oxygen Species and Sarcoplasmic Reticulum Calcium in Pulmonary Arterial Smooth Muscle Cells
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    Chapter 18 Endothelial Cell Reactive Oxygen Species and Ca2+ Signaling in Pulmonary Hypertension
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    Chapter 19 Redox Signaling in the Right Ventricle
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    Chapter 20 Hypoxia and Local Inflammation in Pulmonary Artery Structure and Function
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    Chapter 21 From Physiological Redox Signalling to Oxidant Stress
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    Chapter 22 Emerging Role of MicroRNAs and Long Noncoding RNAs in Healthy and Diseased Lung
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    Chapter 23 Techniques for Detecting Reactive Oxygen Species in Pulmonary Vasculature Redox Signaling
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    Chapter 24 Mitochondrial and Metabolic Drivers of Pulmonary Vascular Endothelial Dysfunction in Pulmonary Hypertension
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    Chapter 25 Subcellular Redox Signaling
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    Chapter 26 Reactive Oxygen Species in COPD-Related Vascular Remodeling
Attention for Chapter 25: Subcellular Redox Signaling
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Chapter title
Subcellular Redox Signaling
Chapter number 25
Book title
Pulmonary Vasculature Redox Signaling in Health and Disease
Published in
Advances in experimental medicine and biology, January 2017
DOI 10.1007/978-3-319-63245-2_25
Pubmed ID
29047101
Book ISBNs
978-3-31-963244-5, 978-3-31-963245-2
Authors

Liping Zhu, Yankai Lu, Jiwei Zhang, Qinghua Hu, Zhu, Liping, Lu, Yankai, Zhang, Jiwei, Hu, Qinghua

Abstract

Oxidative and antioxidative system of cells and tissues maintains a balanced state under physiological conditions. A disruption in this balance of redox status has been associated with numerous pathological processes. Reactive oxygen species (ROS) as a major redox signaling generates in a spatiotemporally dependent manner. Subcellular organelles such as mitochondria, endoplasmic reticulum, plasma membrane and nuclei contribute to the production of ROS. In addition to downstream effects of ROS signaling regulated by average ROS changes in cytoplasm, whether subcelluar ROS mediate biological effect(s) has drawn greater attentions. With the advance in redox-sensitive probes targeted to different subcellular compartments, the investigation of subcellular ROS signaling and its associated cellular function has become feasible. In this review, we discuss the subcellular ROS signaling, with particular focus on mechanisms of subcellular ROS production and its downstream effects.

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
 Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 9 100%

Demographic breakdown

Readers by professional status Count As %
Unspecified 2 22%
Professor 2 22%
Lecturer 1 11%
Other 1 11%
Student > Master 1 11%
Other 1 11%
Unknown 1 11%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 4 44%
Unspecified 2 22%
Nursing and Health Professions 1 11%
Neuroscience 1 11%
Unknown 1 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 April 2018.
All research outputs
#18,574,814
of 23,006,268 outputs
Outputs from Advances in experimental medicine and biology
#3,324
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Outputs of similar age
#311,419
of 421,241 outputs
Outputs of similar age from Advances in experimental medicine and biology
#333
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Altmetric has tracked 23,006,268 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,961 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.1. This one is in the 19th percentile – i.e., 19% of its peers scored the same or lower than it.
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We're also able to compare this research output to 490 others from the same source and published within six weeks on either side of this one. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.

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