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Mendeley readers
Chapter title |
Regulation of Isoform Expression by Blocking Polyadenylation Signal Sequences with Morpholinos
|
---|---|
Chapter number | 12 |
Book title |
Morpholino Oligomers
|
Published in |
Methods in molecular biology, April 2017
|
DOI | 10.1007/978-1-4939-6817-6_12 |
Pubmed ID | |
Book ISBNs |
978-1-4939-6815-2, 978-1-4939-6817-6
|
Authors |
Qiuming Gong, Zhengfeng Zhou |
Editors |
Hong M. Moulton, Jon D. Moulton |
Abstract |
Alternative polyadenylation is increasingly being recognized as an important layer of gene regulation. Antisense-mediated modulation of alternative polyadenylation represents an attractive strategy for the regulation of gene expression as well as potential therapeutic applications. In this chapter, we describe methods to upregulate the functional Kv11.1 isoform expression by blocking intronic polyadenylation signal sequences with antisense morpholinos. |
Mendeley readers
The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 8 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 4 | 50% |
Student > Ph. D. Student | 2 | 25% |
Student > Postgraduate | 1 | 13% |
Student > Master | 1 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 4 | 50% |
Agricultural and Biological Sciences | 3 | 38% |
Medicine and Dentistry | 1 | 13% |