Chapter title |
The Role of Conventional Surgery in Oropharyngeal Cancer
|
---|---|
Chapter number | 14 |
Book title |
HPV Infection in Head and Neck Cancer
|
Published in |
Recent results in cancer research Fortschritte der Krebsforschung Progrès dans les recherches sur le cancer, October 2016
|
DOI | 10.1007/978-3-319-43580-0_14 |
Pubmed ID | |
Book ISBNs |
978-3-31-943578-7, 978-3-31-943580-0
|
Authors |
Wojciech Golusinski |
Editors |
Wojciech Golusiński, C. René Leemans, Andreas Dietz |
Abstract |
Anatomically, the oropharynx can be divided into four subsites: the soft palate, pharyngeal wall, base of tongue, and the tonsillar complex. Surgical access to these tumours is often challenging due to the anatomic localization. For this reason, such tumours were traditionally managed with open surgical techniques, usually involving a mandibulotomy, to provide better visualization and access to the oropharynx, followed by free-flap reconstruction of the oropharyngeal defect. However, the invasiveness of this approach could lead to significant morbidity, including speech, swallowing, and airway dysfunction, in addition to poor cosmetic outcomes. In response, less invasive approaches (Mercante et al. 2013) have been developed including minimally invasive surgical approaches (chiefly transoral surgery) as well as non-surgical methods, primarily radiotherapy, and chemotherapy (Mercante et al. 2013). |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 31 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 7 | 23% |
Student > Bachelor | 4 | 13% |
Student > Postgraduate | 4 | 13% |
Other | 3 | 10% |
Librarian | 3 | 10% |
Other | 6 | 19% |
Unknown | 4 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 12 | 39% |
Agricultural and Biological Sciences | 4 | 13% |
Biochemistry, Genetics and Molecular Biology | 2 | 6% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
Nursing and Health Professions | 1 | 3% |
Other | 6 | 19% |
Unknown | 5 | 16% |