Chapter title |
Risk Factors for Oral Infection with Human Papillomavirus
|
---|---|
Chapter number | 5 |
Book title |
HPV Infection in Head and Neck Cancer
|
Published in |
Recent results in cancer research Fortschritte der Krebsforschung Progrès dans les recherches sur le cancer, October 2016
|
DOI | 10.1007/978-3-319-43580-0_5 |
Pubmed ID | |
Book ISBNs |
978-3-31-943578-7, 978-3-31-943580-0
|
Authors |
Pawel Golusinski |
Editors |
Wojciech Golusiński, C. René Leemans, Andreas Dietz |
Abstract |
Human papillomavirus has been identified as a causative factor for a subset of head and neck carcinomas (HNSCC). The majority of the HPV-positive tumors arises in the oropharyngeal region, and at present, the infection of the human papilloma type 16 is the major cause of the oropharyngeal cancer development. Patients with HPV DNA-positive tumors have been shown to be younger in age and are less likely to have a history of tobacco smoking or alcohol use. The tumors referred to the HPV positivity have been proven to more likely confer better prognosis. Seven percent of the population between ages of 14 and 69 are infected by HPV at any given time within the oral mucosa. However, only about 1 % of those infections is associated with the high-risk cancerogenous types of the virus. Up to date few risk factors of HPV infection have been identified including age, gender and the sexual behavior. Tobacco smoking and immunosuppression have also been reported to play a role in HPV infection. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 34 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 5 | 15% |
Student > Bachelor | 5 | 15% |
Student > Doctoral Student | 3 | 9% |
Researcher | 3 | 9% |
Other | 2 | 6% |
Other | 7 | 21% |
Unknown | 9 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 17 | 50% |
Nursing and Health Professions | 2 | 6% |
Biochemistry, Genetics and Molecular Biology | 2 | 6% |
Agricultural and Biological Sciences | 2 | 6% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
Other | 4 | 12% |
Unknown | 6 | 18% |