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Natural Killer Cells

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Cover of 'Natural Killer Cells'

Table of Contents

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    Book Overview
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    Chapter 1 Natural Killer Cells
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    Chapter 2 Natural Killer Cells
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    Chapter 3 Assessment of NK Cell Metabolism.
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    Chapter 4 Genotyping Single Nucleotide Polymorphisms and Copy Number Variability of the FCGRs Expressed on NK Cells.
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    Chapter 5 Measurement of Average Telomere Length in Ex Vivo Expanded Natural Killer Cells by Fluorescence In Situ Hybridization (FISH) and Flow Cytometry.
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    Chapter 6 In Vitro Assessment of Human Natural Killer Cell Migration and Invasion.
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    Chapter 7 Natural Killer Cells
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    Chapter 8 Microwell-Based Live Cell Imaging of NK Cell Dynamics to Assess Heterogeneity in Motility and Cytotoxic Response.
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    Chapter 9 Assessment of Natural Killer Cell Cytotoxicity Using Image Cytometry Method.
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    Chapter 10 Natural Killer Cells
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    Chapter 11 Using NK Cell Lipid Raft Fractionation to Understand the Role of Lipid Rafts in NK Cell Receptor Signaling.
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    Chapter 12 Natural Killer Cells
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    Chapter 13 The Planar Lipid Bilayer System Serves as a Reductionist Approach for Studying NK Cell Immunological Synapses and Their Functions.
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    Chapter 14 Natural Killer Cells
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    Chapter 15 Natural Killer Cells
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    Chapter 16 Large-Scale Culture and Genetic Modification of Human Natural Killer Cells for Cellular Therapy.
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    Chapter 17 Gene Modification of Human Natural Killer Cells Using a Retroviral Vector.
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    Chapter 18 Modification of Expanded NK Cells with Chimeric Antigen Receptor mRNA for Adoptive Cellular Therapy.
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    Chapter 19 mRNA Transfection to Improve NK Cell Homing to Tumors.
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    Chapter 20 Natural Killer Cells
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    Chapter 21 Engineering Receptor Expression on Natural Killer Cells Through Trogocytosis.
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    Chapter 22 Natural Killer Cells
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    Chapter 23 Natural Killer Cells
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    Chapter 24 Natural Killer Cells
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    Chapter 25 Natural Killer Cells
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    Chapter 26 Noninvasive In Vivo Fluorescence Imaging of NK Cells in Preclinical Models of Adoptive Immunotherapy.
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    Chapter 27 Natural Killer Cells
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    Chapter 28 Generation of BiKEs and TriKEs to Improve NK Cell-Mediated Targeting of Tumor Cells.
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    Chapter 29 Natural Killer Cells
Attention for Chapter 26: Noninvasive In Vivo Fluorescence Imaging of NK Cells in Preclinical Models of Adoptive Immunotherapy.
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Chapter title
Noninvasive In Vivo Fluorescence Imaging of NK Cells in Preclinical Models of Adoptive Immunotherapy.
Chapter number 26
Book title
Natural Killer Cells
Published in
Methods in molecular biology, January 2016
DOI 10.1007/978-1-4939-3684-7_26
Pubmed ID
Book ISBNs
978-1-4939-3682-3, 978-1-4939-3684-7
Authors

Srinivas S. Somanchi Ph.D., Srinivas S. Somanchi

Editors

Srinivas S. Somanchi

Abstract

Preclinical animal models play a vital role in developing novel adoptive immunotherapies for cancer. In these in vivo models, it is essential to track the adoptively transferred cells to understand their tissue localization (biodistribution) in order to correlate with observed therapeutic outcomes as well as to develop novel approaches to promote homing to tumors or organs of interest. This chapter describes a simple and quick method for fluorescence labeling and in vivo imaging of adoptively transferred NK cells in small animal models.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 8 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 50%
Professor 1 13%
Student > Doctoral Student 1 13%
Unknown 2 25%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 2 25%
Immunology and Microbiology 2 25%
Pharmacology, Toxicology and Pharmaceutical Science 1 13%
Medicine and Dentistry 1 13%
Unknown 2 25%